Penicillin antibiotics have bactericidal properties, low toxicity, and a broad spectrum of antimicrobial action. In addition, these drugs are affordable and cheap.
Benzylpenicillin sodium salt is included incategory "penicillin antibiotics". The drug is acid-resistant and is destroyed under the influence of intestinal r-lactamase (enzymes that completely or partially block the activity of antibiotics). The use of the drug is intravenous, intramuscular, endolyumbalnoe. Immediately before the introduction of the drug is dissolved. The drug has a high penetrating ability with respect to the mucous membranes of the heart, kidneys, intestinal wall, synovial and pleural fluid. There is a bad passage through the BBB (hemato-encephalic barrier). Duration of action of the drug from three to four hours. It shows activity mainly in relation to gram-positive microflora (cocci), causative agents of diphtheria, syphilis, anthrax and others. The drug is shown in pneumonia, purulent-septic infections, abscesses, diphtheria, syphilis, meningitis and other pathologies.
Benzylpenicillin potassium salt has all the above properties. It differs from the sodium salt in the limited manner of administration (only intramuscularly).
Phenoxymethylpenicillin (smallpox, penicillin-Fau)also belongs to the category "penicillin antibiotics". It differs from previous preparations by acid resistance. In addition, the drug is characterized by a high long-term concentration in the blood, as well as good absorbability. This antibiotic is indicated for infectious diseases in mild forms, triggered by pathogens that are sensitive to penicillins.
In the category of antibiotics penicillinBicillin is also included. This prolonged drug is intended only for intramuscular use. The drug is indicated for the prevention of surgical infections, recurrence of rheumatism, as well as for therapeutic purposes in syphilis, pneumonia and other pathologies.
Penicillin group antibiotics also include drugs with a wide range of effects.
One of these medicines is Ampicillin.The drug is acid resistant. Able to be absorbed into the bloodstream quickly, penetrate into the body fluids and tissues, with the exception of cerebrospinal fluid.
Ampioks has a wide rangeantimicrobial effects, as well as a bactericidal effect on penicillinase-producing staphylococcus. This medication is prescribed for purulent-septic and ENT infections, infections of the respiratory organs, urinary and biliary tract, sepsis, abscess, meningitis, peritonitis and other diseases.
A wide range of effects also hasdrug Carbenicillin. The drug is very effective against infections, triggered by a pyocyanic stick and gram-negative bacteria, acid resistant. Not resistant to p-lactamase (blocking enzymes). The drug is not absorbed in the gastrointestinal tract, therefore its use is only intravenous or intramuscular.
Semisynthetic penicillin with a wide range of effects is Amoxicillin. Bio-assimilation of the drug is more than 90%. Amoxicillin tablets can be dissolved, swallowed or chewed.
It should be noted that, as a rule, drugspenicillin row tolerated by patients quite well. Possible mild side effects in the form of allergic rashes on the skin, vomiting, nausea, and stool disorders.
Broad-spectrum antibiotics often suppress not only pathogenic microflora, but also beneficial.
Some pathogenic bacteria are resistant to many drugs. Therefore, scientists are creating more modern antibiotics that affect new strains.
