Drug "Gliformin" refers to the groupbiguanides. It is a hypoglycemic drug that reduces the absorption of glucose and simultaneously increases the sensitivity of some tissues to insulin. From the materials of this article, you will learn in what dosage Glyformin is prescribed for diabetes mellitus, the cost of the drug and reviews of real patients.
Composition and form of release
The drug is sold in the form of tablets, which can be of two types:
- Flat-cylinder pills with a white chamfer (0.5 g of the active substance). Packaged in 10 pieces in a cellular packaging.
- Pills in a film shell cream color (0.85 or 1 g of the active substance). Prepacked in polypropylene cans of 60 pieces.
The active ingredient is metformin hydrochloride.
pharmachologic effect
"Gliformin" in diabetes should be taken exclusively orally. The mechanism of the drug on the system of internal organs has not been studied until the end.
Penetrating into the body, the active active ingredient is involved in the following processes:
- Suppression of the formation of glucose molecules in the liver.
- Activating the breakdown of carbohydrates.
- Reducing the amount of glucose coming from the intestines.
The use of the drug "Gliformin" with sugardiabetes and obesity leads to a decrease in appetite, body weight. The instructions indicate that the drug contributes to the gradual dissolution of blood clots and prevents adhesion of platelets.
Metformin hydrochloride absorbs quicklycells of the digestive tract. The limiting concentration of the active active ingredient is fixed after two hours from the moment of administration. Its bioavailability is approximately 50-60%. The drug does not enter into connection with plasma proteins, gradually accumulates in the systems of internal organs. From the body, the substance is eliminated almost unchanged.
Indications for use of the drug "Gliformin"
Tablets instructions for use recommends taking patients with the following pathologies:
- Diabetes mellitus type II, when diet therapy and sulfonylurea drugs are ineffective.
- Type I diabetes mellitus (supplement to standard insulin therapy).
During treatment, constant monitoring of the kidneys is necessary, it is recommended to check the plasma lactate parameters every six months.
Mode of application
What dosage prescribed "Gliformin" withdiabetes? According to the instructions, the tablets should be taken during / after meals, while they need to drink water. The specific dosage and duration of the course of treatment is prescribed by the doctor, taking into account the patient's blood glucose.
At the initial stage of therapy (first 15 days)dosage is not more than 1 g per day. Then it is gradually increased. Maintenance dose usually does not exceed 2 g per day. It is evenly divided into several techniques.
For older patients, the daily dose of the drug is not more than 1 g.
Adverse Events
When a doctor prescribes "Gliformin" in diabetes, reviews of real patients allow us to evaluate the effectiveness of the drug. Like other medicines, it can cause a number of side effects:
- Endocrine system: hypoglycemia.
- Circulation: anemia.
- Allergic reactions: rash, urticaria.
- Metabolism: hypovitaminosis.
- Gastrointestinal system: lack of appetite, nausea, taste of metal in the mouth, vomiting, diarrhea.
If adverse reactions occur, you should refuse to take pills for some time and consult a doctor.
Contraindications
The instructions for the drug says that its reception is not recommended in the following conditions:
- diabetic coma;
- ketoacidosis;
- pulmonary / heart failure;
- chronic liver disease;
- myocardial infarction;
- hypersensitivity to the components of the drug;
- pregnancy and lactation.
With extreme caution should be used "Gliformin" from diabetes in pathologies of infectious nature, before major operations.
Drug Interactions
According to the instructions, while applyingwith insulin, nonsteroidal anti-inflammatory drugs, sulfonylurea derivatives, beta-blockers does not exclude the potentiation of the action of Glyformin.
Its effectiveness can be significantly reduced due to additional treatment with glucocorticosteroids, oral contraceptives, thyroid hormones, nicotinic acid derivatives, diuretics.
Price and storage conditions
The drug should be stored at a temperature of up to 25 degrees in a place protected from children. The shelf life is 3 years, and for tablets in the film coating - 2 years.
How much does Gliformin cost?In diabetes, the price of drugs plays an important role for many patients. The drug described in the article is relatively inexpensive. For the packaging of tablets in the film shell will have to pay a little more than 300 rubles. Pills with dividing chamfer (0.5 g of the active substance) are cheaper - about 150 rubles.
Analogues
When they buy the drug "Gliformin"application, instructions, reviews - this is the first thing that patients pay attention to. Due to the wide range of contraindications for many, the drug is not suitable. It is possible to pick up a medicine similar in pharmacological properties after consultation with a doctor.
Among the analogues that most closely correspond to "Gliformin" in the content of the active substance, the following are distinguished: "Diaberit", "Metformin", "Glucoran".
Reviews of patients and doctors
Many patients who have been assigned thisdrug for treatment, noted a high probability of overdose. In most cases, it is caused by improper use of the drug. Overdose can cause the so-called lactic acidosis. Its main symptoms are muscle pain, vomiting and nausea, impaired consciousness. If the patient has such signs, it is recommended to stop taking the medication and seek medical help.
On the part of specialists, reviews are in the majoritypositive cases. That is why so often prescribed "Gliformin" for diabetes. The price of the drug is low, it can be purchased at almost every pharmacy. If you strictly follow the instructions, the likelihood of side effects is low. Doctors warn that during the entire course of treatment, it is necessary to be tested for serum creatinine 2-3 times a year. During therapy, you should abandon alcohol and medication, in the composition of which there is ethanol.
Let's sum up the results
Сахарный диабет — это достаточно распространенное a disease that is increasingly being diagnosed in young people today. For his treatment, doctors prescribe various medications. "Gliformin" also refers to their number. It is a hypoglycemic drug that is responsible for increasing the sensitivity of tissues to insulin. If taken in accordance with the instructions and as prescribed by a physician, there should be no side effects. It is equally important to take into account the contraindications of the drug.
