Modern people very often experience neuroses,irritability and stress. Against the background of such conditions, the general state of health and overall health in the person noticeably worsen. The consequences of neuroses are insomnia, fatigue, lethargy, hypertension, tachycardia, spasms and so on. Therefore, with severe stress and irritability, it is very important to take a drug in time, which helps to calm a person.
The most popular remedy with such properties is the "Korvalkaps" medication. Instructions for use, the form, cost and features of the medication are discussed below.
Form release, composition, description, packaging
The drug "Korvalkaps", reviews of which are described below, goes on sale in the form of soft capsules. They are placed in blisters and cardboard packages.
The composition of this medicine includes such basiccomponents, such as phenobarbital and ethyl ester of alpha-bromoisovaleric acid. Also, the medicament in question contains mint oil, trihydrate, sodium acetate, purified water and polyethylene glycol 200 (excipients).
With regard to the drug coating, it consists of glycerol, gelatin, propyl parahydroxybenzoate and methyl parahydroxybenzoate.
Basic properties
What antispasmodics are you aware of? "Korvalkaps" is the most effective medication, which acts not only spasmodically, but also soothing.
The effectiveness of this tool is determined by the properties of the components that make up its composition.
The ethyl ester of alpha-bromoisovaleric acidshows reflexive soothing and antispasmodic properties. Such features of the drug are caused by stimulation of the nasopharynx and oral cavity receptors, as well as by a decrease in the excitability (reflex) in the central nervous system, increased braking processes in the subcortical structures and neurons of the cerebral cortex, decreased activity of the vasomotor centers and local spasmolytic effect on the smooth muscles of the vessels.
With regard to such an ingredient asphenobarbital, it helps suppress the activating effect of the centers of the reticular formation of the medulla oblongata and the midbrain on the cerebral cortex. As a result, the exciting currents decrease, which affect the subcortical structures and the cortex of the brain.
According to experts, it is these properties of the drug (depending on its dosage) that cause a hypnotic or sedative effect.
Какие еще свойства присущи медикаменту "Corvalcaps" whose price is listed below? This drug reduces total blood pressure, reduces the excitatory effect on peripheral and coronary vessels, vasomotor centers, and also relieves and prevents vascular spasms, including heart.
Kinetic parameters
Где абсорбируются капсулы (таблетки) «Корвалкапс»?When administered this drug begins to be absorbed in the sublingual area. Its bioavailability is very high and is approximately 60-80%.
The effect of the drug develops much faster (after about 5-12 minutes) when it is held in the oral cavity (sublingual absorption), that is, after cutting the capsule.
If the drug is swallowed as a whole, its effect is noted after 20-45 minutes and lasts for 3-6 hours.
In patients who have previously taken drugsbarbituric acid, the effectiveness of the drug is reduced. This is due to the accelerated metabolism of phenobarbital in the liver (it is in this organ that barbiturates induce the induction of enzymes).
In the elderly and patients with cirrhosisthe metabolism of the considered drug is reduced, therefore, in this category of people, the half-life of the drug is extended. This requires lower dosages and longer intervals between capsules.
Indications
Preparations containing phenobarbital and ethyl alpha-bromoisovaleric acid ester (for example, Korvalcaps) are used in:
- neurosis with increased irritability;
- vegetative-vascular dystonia and hypertensive disease (in combination therapy);
- insomnia;
- mild spasms of the coronary vessels and tachycardia;
- intestinal spasms caused by neurovegetative disorders (as an antispasmodic).
Contraindications
Preparations containing ethyl alpha-bromoisovaleric acid ester and phenobarbital (including “Korvalkaps”) do not recommend to be administered when:
- pronounced disorders in the kidneys or liver, hepatic porphyria;
- hypersensitivity to bromine and drug components;
- heart failure severe.
Drug "Korvalkaps": instructions for use
In what dosages is the prescribed drug prescribed to patients? You will learn about it right now.
Soft capsules "Corvalcaps" take only inside. The use of this tool does not depend on the time of the meal.
The drug is prescribed in one capsule three times a day.a day, washing it down with ordinary water. If it is required (for example, in case of severe tachycardia or spasms of the coronary vessels), then a single dosage of the drug can be increased to two capsules.
How long should the drug be consumedCorvalcaps? Instructions for use states that the duration of treatment with this drug is determined by the doctor (depending on the tolerance of the drug and the clinical effect).
Cases of overdose
What will happen if you take antispasmodic drugs in high doses? Such patient behavior may contribute to the development of addiction, withdrawal symptoms and psychomotor agitation.
We can not say that the abrupt cessation of medication causes withdrawal syndrome.
Signs of overdose with the drug "Corvalcaps"are: confusion, depression of the central nervous system, dizziness, drowsiness and ataxia. In severe poisoning, the patient may have impaired breathing, arrhythmia, tachycardia, coma, collapse, and decreased blood pressure.
To eliminate these conditions, symptomatic treatment is used.
Side effects
The drug "Corvalcaps Extra" is tolerated by patients quite well. In some cases, the medication in question may cause such side effects as:
- drowsiness, allergic reactions;
- slight dizziness, discomfort in the abdomen;
- decreased concentration, nausea;
- slow heart rate.
These reactions are eliminated by reducing the dosages of the drug.
With prolonged use of the drug in a patientThere may be a dependence on the drug and the phenomenon of bromism. The following symptoms also develop: depression, CNS depression, acne, apathy, hemorrhagic diathesis, rhinitis, confusion, conjunctivitis, impaired coordination.
Interaction with other means
Can I use Corvalcaps capsules with other drugs? Instructions for use states that the effect of the remedy in question is enhanced by drugs of the central inhibitory type.
Part of the drug phenobarbital mayeasy to induce liver enzymes. In this regard, it is undesirable to combine it with drugs that are metabolized in the liver (that is, with griseofulvin, coumarin derivatives, oral contraceptives, glucocorticoids), since their effectiveness will be reduced due to the high level of metabolism.
Capsules "Corvalcaps" increase the effect of sleeping pills, painkillers and local anesthetics (due to the content of barbituric acid derivatives).
With the combination of the above-mentioned drug with valproic acid, its effect is enhanced.
Parallel administration of the drug with methotrexate increases the toxicity of the latter.
Alcohol enhances the effect of "Corvalcaps", as well as increases its toxicity.
Special Information
Capsules "Korvalkaps" produces Kiev Vitamin Factory.
In the treatment of this tool should avoid the use of alcoholic beverages.
It is forbidden to use the drug for a long time due to the possible development of dependence on it.
With extreme caution, this medicine is prescribed for arterial hypotension.
Рассматриваемый медикамент содержит фенобарбитал.This component can cause disturbances in the speed of psychomotor reactions of a person and his coordination. Therefore, taking capsules to people who work with dangerous machinery (drivers of vehicles) should be very careful.
Experience in the use of the drug in children is absent.
Cost and reviews
How much do Corvalcaps capsules (Kiev Vitamin Factory) cost? The price of this medicine is about 80-120 rubles.
Consumer reviews report that the drug in question is very effective in neurosis and irritability. In addition, the reception of this tool relieves spasms of blood vessels and intestines.
Also, the advantages of this medication include its low cost and availability in all pharmacies.
