The drug "Sirdalud" (Sirdalud) is available in tablets containing four milligrams of the active substance in blisters of thirty pieces.
Pharmacological effects of the drug "Sirdalud" instructions for use are described as follows:
The active substance of this tool -tizanidine, which is a muscle relaxant, has a central action that affects the muscles of the skeleton. He also has a moderate central anesthetic effect.
Use of the drug is justified in acute andchronic spastic pathologies of both central and spinal genesis. Thanks to the “Sirdalud” tool, the strength of arbitrary contractions of the skeletal muscles is increased and the spasms and clonic convulsions are reduced. Absorption of the drug "Sirdalud" occurs quickly, almost completely. The maximum concentration in the blood is reached within one hour after administration. The average bioavailability is thirty-four percent. The half-life of the drug is on average from two to four hours. Excreted through the kidneys (up to seventy percent) as metabolites and only two point seven percent in unchanged form. Eating together with the reception of this tool does not affect its pharmacokinetics.
Drug "Sirdalud." Indications for appointment:
Muscle spasms of the skeleton, which are caused byneurological diseases such as degenerative pathologies of the spinal cord, chronic myelopathy, cerebral palsy, disorders of cerebral circulation. Also, with painful muscle spasms associated with static and functional pathologies of the spine (with cervical and radicular syndromes), the postoperative period after intervertebral hernia operations of osteoarthrosis of the hip joint, and the like.
The method of use for the drug "Sirdalud" instructions for use gives the following:
Doses are selected by the attending physician individuallyorder, based on the response to the drug in a patient and the clinical picture of the disease. The initial volume is given no more than six milligrams per day. It is divided into three doses, after three to seven days can be increased by two to four milligrams.
Usually, the therapeutic dose becomesoptimal, starting with twelve to twenty four milligrams per day, divided into three or four doses, in equal time. Exceed the dosage of the drug "Sirdalud" instructions for use in a range higher than thirty-six milligrams per day, does not recommend. In the case of treatment of painful muscle spasms, “Sirdalud” is applied two to four milligrams three times a day. In the case of pronounced spasms, an additional dose of up to four milligrams of the drug is allowed at night.
For the treatment of elderly patients with medication"Sirdalud" instructions for use recommend careful medical supervision, since there is very limited clinical experience in the treatment of this category.
In pediatrics, the use is not recommended, because experience in treating children with this drug is insufficient.
In case of renal failure the drug "Sirdalud"instructions for use recommends prescribing, starting with two milligrams per day at a time. Then gradually increase the dosage, given the portability and effectiveness.
Drug "Sirdalud." Description of side effects:
Rarely there are violations of the gastrointestinal tract, drowsiness, weakness, slight hypotension, dry mouth, dizziness.
Contraindications to the use of the medication "Sirdalud" the following:
Severe abnormal liver function, hypersensitivity to the drug components, possible combination of tizanidine with fluvoxamine.
p>