Ursodeoxycholic acid is an effective choleretic and hepatoprotective agent

Ursodeoxycholic acid is a remedyexerting choleretic and hepatoprotective effects. It is produced in the form of capsules, is included as an active component in the composition of many choleretic drugs.

Pharmacological properties

By origin, the remedy isderived bile acid. It has, in addition to the protective and choleretic action, immunomodulatory properties, helps reduce the formation of cholesterol in the blood and gallstones. The drug contributes to the stabilization of liver cells, gives them greater stability when exposed to an aggressive environment. Ursodeoxycholic acid normalizes the activity of lymphocytes, eliminates the expression of antigens in the hepatic ducts and cells. Specialists speak positively of the remedy as a drug that reduces liver fibrosis in fatty alcoholic degeneration, cystic fibrosis, biliary primary cirrhosis. The absorption of the drug occurs in the small intestine, and the maximum concentration in the blood is achieved three hours after ingestion.

Indications for use of the drug "Ursodeoxycholic acid"

Preparations "Ursodex", "Ursoliv", "Urso","Ursofalk", "Ursosan", in which the substance is an active component, is prescribed for the complex treatment of gallstone disease, in cases where the pathology is caused by elevated cholesterol, and removal by endoscopy or surgery is not possible.

Stones are pre-crushed if their sizeexceeds 2 cm. Ursodeoxycholic acid is used in chronic forms of active hepatitis, occurring with bile stasis, in cystic fibrosis of the liver, in biliary primary cirrhosis or reflux esophagitis, acute hepatitis. Reviews say that the remedy helps with cholecystopia and biliary dyskinesia. In addition, the drug is prescribed in order to prevent stagnation of bile while taking cytotoxic drugs, contraceptives.

Ursodeoxycholic acid: instructions, price

Лекарство можно использовать в любом возрасте, even a newborn. The dosage is determined by the doctor individually for each patient, depending on the weight and severity of the manifestations of the disease. The average volume of the drug is 10 mg per kg. It is required to consume once in the evening.

Once every three months during treatment it is necessarycheck the level of liver enzymes. When removing gallstones every six months, examine the liver and biliary tract. The cost of the drug is 400 rubles.

Contraindications and side effects

It is prohibited to use the product in case of acuteinflammations of the gallbladder and excretory tract (cholangitis, cholecystitis). Prescriptions are not made in case of liver cirrhosis, renal dysfunction, ulcerative nonspecific colitis, and individual intolerance. Ursodeoxycholic acid may temporarily increase the level of liver enzymes. In rare cases, the drug causes diarrhea, calcification of gallstones, skin allergic manifestations.