The drug "Orungal" refers to syntheticantifungal agents derived from triazole. The drug has a fairly wide range of effects. The active ingredient is itraconazole. The medicine is produced in the form of a solution and capsules.
Antifungal activity of the drug "Orungal"(expert reviews confirm this) is based on its ability to disrupt ergosterol synthesis in the fungal cell membrane. Itraconazole (the active ingredient of the drug) is active against infections provoked by dermatophytes, yeast and yeast-like fungi. In this case, the fungi of the genus Candida exhibit the least sensitivity.
Medication "Orungal" (patient reviews areconfirm) is effective in fungal keratitis, ringworms, oral and vulvovaginal candidiasis. The drug is used for pityriasis versicoloris, thrush in the esophagus or oral cavity in patients with HIV infection and immunodeficiency.
Medicine "Orungal" (reviews of doctorsconfirm) is used for onychomycosis, provoked by yeast or dermatophytes. The indications include systemic mycoses: systemic candidiasis and aspergillosis, histoplasmosis, cryptococcosis (including cryptococcal meningitis), paracoccidioidomycosis, sporotrichosis, blastomycosis, and other rarely encountered tropical or systemic mycoses.
The drug "Orungal" (feedback from experts isconfirm) should be used as prophylaxis of fungal infections in patients with malignant blood pathology or in bone marrow transplants with an increased risk of neutropenia.
Capsules are recommended to be taken after meals.
When vulvovaginal candidiasis is prescribed for 200milligram twice a day one day. As an alternative regimen, the doctor may suggest the patient take two hundred milligrams once a day for three days.
When pityriasis lichen is prescribed 200 mg once a day. Duration of use - a week.
For dermatomycosis of smooth skinrecommend two hundred milligrams once a day. The duration of treatment is a week. An alternative regimen of application is one hundred milligrams per day for fifteen days.
With lesions of highly keratinized areasskin (feet or hands) is prescribed two hundred milligrams twice a day for fourteen days or one hundred milligrams once a day for thirty days.
When fungal keratitis is recommended to take200 milligrams once a day. The treatment lasts for twenty one days. In accordance with the clinical picture, the duration of treatment can be adjusted by a doctor.
For oral candidiasis, 100 mg is prescribed once a day for fifteen days.
The treatment of the fungus of the toenails is carried out according tomethod of pulse therapy. The dosage of the drug at the same time sets the doctor. Probably, an ointment from nail fungus can additionally be prescribed. The drug in this case will be selected in accordance with personal characteristics.
Not recommended medication "Orungal" during pregnancy and lactation. The use of the drug can provoke abnormal development of the fetus.
Medication may cause constipation, diarrhea,nausea, hepatitis. In some cases, the drug "Orungal" can provoke peripheral neuropathy, dizziness, headache. The use of medication can cause anaphylactic reactions, angioedema, urticaria, pulmonary edema.
The drug "Orungal" is contraindicated inhypersensitivity, while the use of funds "Lovastatin" and "Simvastatin", as well as ergot alkaloids. In addition, the simultaneous use of the drug with the medicines Terfenadine, Mizolastin, Astemizol, Tsisaprid, Sertindol, Pimozide, Quinidine, Dofetilide, Levometadone is not recommended.
Before taking the drug "Orungal" should consult with experts.