Tablets "Preductal" instruction describes as a drug that improves metabolism in the myocardium and neurossensory organs during ischemia. The active substance is trimetazidine hydrochloride.
Mechanism of action
Means "Preductal", indications for usewhich will be described below, contributes to the normal functioning of ion channels in the membranes. The drug also provides for the transfer of sodium and potassium ions, maintaining cell homeostasis. The drug reduces the size of myocardial damage, without having a direct effect on hemodynamic parameters. Against the background of angina pectoris, the drug contributes to an increase in coronary reserve, thus slowing the onset of ischemia, provoked by physical overstrain. The tool provides for limiting fluctuations in blood pressure, without a significant change in the frequency of heart contractions. In patients with ischemic dysfunction while taking the medication, improvement of the contractile function in the left ventricle is noted.
The drug "Preductal". Application. Price
The cost of medication in pharmacies from 700 rubles.Under what pathologies is Preductal prescribed? Indications for use of this drug are as follows: coronary artery disease, cochleo-vestibular disorders of ischemic nature (tinnitus, dizziness, etc.). The drug is recommended for the prevention of angina attacks (in combination with other drugs or as a single agent). For chorioretinal vascular disorders with the ischemic component, the drug Preductal is also prescribed. Indications for use, the severity of the pathology, as well as patient tolerance are the main criteria in determining the duration of medication.
Dosing regimen
The drug is drunk during the meal.It is advisable to take medicine in the morning and evening. The recommended dose is 1 tab. 2 p / day. The drug should not be chewed or crush. The duration of the therapy or prophylaxis is established personally by the specialist.
Side effects
Means "Preductal", indications for usewhich are listed above, can trigger a number of complications. In particular, abdominal pain, dyspepsia, constipation, vomiting and nausea are noted on the basis of therapy or prophylaxis. Patients may develop asthenia, dizziness, tremor, and headaches. Undesirable effects include various motor impairments (reversible, as a rule, after discontinuation), sleep disorder. A frequent side effect is an allergic reaction, manifested by skin rashes, irritation, urticaria. In some cases, angioedema may occur. On the basis of taking the medication, extrasystole is likely, tachycardia, palpitations, orthostatic hypotension with dizziness, general weakness, loss of balance.
Contraindications
Do not prescribe medication to patients with renalinsufficiency, with hypersensitivity, Parkinson's disease, motor disorders associated with restless legs syndrome. Not recommended for patients under 18 years of age. The feasibility of using the drug during pregnancy or during the feeding period is determined by a specialist.
