Testosterone undecanoate is an ether of natural androgen, testosterone. About the form in which this tool is produced, why and how it is used, we will tell in the presented article.
You will also find out what properties the substance has, whether it has contraindications and side effects.
Release form, description and packaging
Testosterone undecanoate is available in various forms:
- Gelatin capsules that contain the active ingredient. They are packaged in blisters and cardboard boxes, respectively.
- Oily and clear solution with yellowishtint for intramuscular injection. 1 ml of this preparation contains 250 mg of testosterone undecanoate. As auxiliary elements use: benzyl benzoate and purified castor oil. The drug goes on sale in amber glass ampoules, which are placed in cardboard boxes with an ampule holder glued in.
Pharmacology
How to get testosterone undecanoate? Reviews of experts report that such an active form of the drug is formed by splitting the side chain.
Testosterone is the male sex hormone, which has the entire spectrum of biological activity that is necessary for the formation and maintenance of androgenic functions.
The synthesis of this substance occurs in the testicles, andalso in the adrenal cortex. During prenatal development, as well as in early childhood and during puberty, this element contributes to the formation of male characteristics and sexual organs. Subsequently, the mentioned hormone provides support for androgen-dependent functions and the male phenotype.
Inadequate secretion of this substance leads tothe development of hypogonadism. Its symptoms include erectile dysfunction, depressive mood, decreased sexual desire, increased fatigue, regression, the absence or underdevelopment of secondary sexual characteristics.
Also, such representatives of the stronger sex increases the risk of osteoporosis.
Properties
Testosterone undecanoate is prescribed to increase insufficient levels of endogenous testosterone, as well as reduce the signs of hypogonadism.
The nature of this drug is due to the following properties:
- androgenic (affects the epididymis, seminal vesicles, prostate gland);
- protein-anabolic (affects the bones, muscles, kidneys, the hematopoietic system, the liver).
In men who suffer from hypogonadism,Testosterone undecanoate reduces the mass of adipose tissue and increases lean body mass. It also prevents loss and promotes bone growth, improves sexual function and has a positive psychotropic effect.
Indications for use
What is testosterone use for?undecanoate? The instruction states that for the representatives of the stronger sex such agents are used as hormone replacement therapy for disorders caused by secondary or primary testosterone deficiency, including postkastratsionny syndrome, hypopituitarism, eunuchoidism, endocrine impotence and some types of infertility caused by impaired spermatogenesis, as well as climacteric disorders in men (for example, with a decrease in physical and mental activity, libido).
In transsexuals with a change of gender (on male), this medication is prescribed for masculinization.
Testosterone undecanoate can also be used for osteoporosis, which is caused by androgen deficiency.
Contraindications
Testosterone undecanoate (ampoules and tablets) may not be used for:
- androgen-dependent prostate carcinoma;
- hypercalcemia, which is accompanied by malignant tumors;
- androgen-dependent carcinoma of the breast in the representatives of the stronger sex;
- hypersensitivity to the main substance or any auxiliary component of the drug;
- liver tumors in history or at present.
It should also be noted that testosterone undecanoate (Nebido) is not prescribed to women.
With extreme caution, it is recommended for patients with apnea syndrome and children in adolescence.
Method of use of tablets
Pills that increase testosterone in menmust be taken only in the process of eating. At the same time food should not contain too much fat. Otherwise, the absorption of the drug through the lymphatic system will be maximized.
When taking pills on an empty stomach, their absorption is minimal.
If the drug was prescribed to increase testosterone in the stronger sex, then it is prescribed twice a day.
To increase the level of androgens, the medication is taken in a dosage of 120-160 mg every day for 3 weeks.
Для выраженного анаболического воздействия Experts recommend using high doses of medication. In this case, you must take 240 mg of the drug every day. It should be borne in mind that this dosage may lead to the development of adverse reactions.
The use of injectable form of the drug
The introduction of the drug "Nebido" in a dosage of 1 gTestosterone undecanoate (i.e., 1 ampoule) is administered once a day for 10–15 weeks. This frequency of injections provides support for a sufficient level of the hormone, which does not cause its accumulation.
The drug is administered intramuscularly immediately after opening the ampoule. The injection is done slowly. At the same time ensure that the drug does not fall into a blood vessel.
Before starting treatment, consult a doctor. The latter is obliged to determine the amount of testosterone in serum.
The interval between the first injections should be at least 6 weeks.
At the end of this interval, the testosterone concentration in the blood should be checked. If its level is below normal, then the interval between injections is to be reduced.
If the concentration of testosterone is high, then it is necessary to consider increasing the interval.
Side effects
After taking the pills, the following undesirable effects may develop:
- frequent erections, active sexual development, an increase in the genitals of adolescents;
- sodium and water retention;
- increased libido;
- oligospermia;
- priapism and other signs of sexual stimulation;
- nausea and dizziness.
With intramuscular administration of the drug in men are observed:
- increased hemoglobin, hypersensitivity;
- weight gain, hypercholesterolemia;
- increased appetite, polycythemia;
- increased red blood cell count, depression;
- insomnia, migraine, anxiety;
- aggressiveness, headache, irritability;
- flushing, dizziness, hypertension;
- bronchitis, shortness of breath, sinusitis, diarrhea;
- rash, arthralgia, papular rash, pain in the limbs;
- itching, muscle tension, dry skin, etc.
Price and analogy
Testosterone undecanoate in a pharmacy can be purchased for 1000-1200 rubles.
Analogs of this medicine are suchdrugs like "Andriol", "Androkson" and "Virigen." To determine which of the following means should be used in the process of therapy, only an experienced specialist can based on the data of medical examination and analyzes.
Men reviews about the drug
Testosterone undecanoate - a drug that oftenused as hormone replacement therapy. Most men who take this medication speak of it exclusively on the positive side. According to their reports, testosterone tablets is less effective than a similar drug, but in an injectable form. Therefore, many patients are trying to purchase the product in ampoules.
Although there are men whoThey say that testeorine undecanoate tablets act no worse than injections. Moreover, they are much more convenient, since you can take them not only at home, but also at work, at rest, and so on.
