Drug "metoprolol" instructions for usebelongs to the group of cardioselective beta-blockers with antiarrhythmic, hypotensive and antianginal effects. Taking this medication allows for a relatively short time to slow down AV conduction, reduce the automatism of the sinus node, the excitability and contractility of the myocardium, as well as reduce heart rate, cardiac output and the need of myocardium for oxygen supply. In addition, the cardio-selective drug Metoprolol, the price of which is about fifteen to twenty rubles, effectively suppresses the stimulating effect of catecholamines on the heart during psychoemotional and physical exertion. As for the main pharmacokinetic characteristics of this drug, its greatest concentration in plasma begins to be noted after about one to two hours, and the time of the so-called half-life is on average from three to seven hours.
The hypotensive drug Metoprolol is produced.(instructions for use are always included) in the form of round tablets of white-cream color and in the form of a solution intended for subsequent intravenous administration. The composition of this cardioselective medication as an active ingredient is metoprolol tartrate. The tablets additionally contain lactose monohydrate, microcrystalline cellulose, povidone, calcium stearate, talc and crospovidone.
Use antianginal and antiarrhythmicMetoprolol, the manufacturer’s instructions for use, recommends for the treatment of patients suffering from angina (including post-infarction), arterial hypertension and arrhythmia (including supraventricular type tachyarrhythmia). In addition, quite often doctors prescribe this antihypertensive drug in order to prevent migraine attacks. In the complex treatment of thyrotoxicosis, it is also recommended to start taking the cardio-selective agent Metoprolol. Indications for administration include maintenance therapy after myocardial infarction. In this case, the treatment plan in each case is established exclusively by the doctor on the basis of the obtained tests.
As for the list of main contraindicationsto receive this cardio-selective medication, here first of all it is necessary to select hypersensitivity to metoprolol tartrate, as well as an allergic reaction to any of the auxiliary components. People with heart failure, atrioventricular block, severe sinus bradycardia, or sinoatrial blockade should also not be taken with the metoprolol antiarrhythmic drug. The instructions for use also does not recommend to prescribe this antihypertensive agent in case of weakness of the sinus node, disturbances in the peripheral circulatory system or arterial hypotension. With great care, it is necessary to use this medicine in the case of hyperthyroidism, diabetes mellitus, bronchial asthma, pheochromocytoma, hypoglycemia, myasthenia, emphysema, psoriasis, metabolic acidosis, non-allergic bronchitis or depression.
