«Фурамаг» относится к производным нитрофурана antimicrobial agents. One capsule of the drug contains 50 mg of the active substance furazidina and excipients, talc potassium carbonate and magnesium carbonate.
Pharmacology
Drug "Furamag" - this is an antibiotic, he very resistant to gastric acidic environment, has high bioavailability, withthis does not change the color of urine, in the kidneys there is a high concentration. Based on the composition of the drug "Furamag", the instruction refers it to complex means, it consists of furazidine and magnesium carbonate in a ratio of 1: 1, the presence of the latter affects its pharmacological properties.
Действует «Фурамаг» как высокоэффективное anti-infective agent. What matters is the fact of its high concentration in the lymph, this creates an obstacle to the transmission of infection through the lymphatic ducts. The instruction also indicates high accumulations of the substance “Furamag” also in the bile, in slightly smaller quantities in blood serum, in the liver, in the portal vein. Repeated use of the drug does not cause resistance in microorganisms.
The main principle of the drug"Furamag" is its ability to inhibit nucleic acids. The drug starts in the cell of the microorganism such irreversible processes that inevitably lead to its death. "Furamag" reduces the toxicity of some microorganisms, this is important, because even before its action leads to their death, an improvement in the patient's condition is observed.
The drug "Furamag" has a wideradius of action, it shows high activity against many grams of positive and negative bacteria, even those that remain resistant to other antibiotic drugs. Due to this property, the drug "Furamag" instruction recommends its use. Even if it was not possible to achieve high efficacy from other antibacterial drugs.
To the many advantages of the drug "Furamag" instructionadds its beneficial effect on the immune system (unlike other antibiotics that suppress it). The maximum concentration of the drug in the blood is maintained for 8 hours, after 4 hours you can detect the presence of the active substance in the urine, the drug is excreted by the kidneys, there are recommendations for receiving after a meal, because then the bioavailability of Furamag increases.
Judging by the pharmacodynamics can be said about medical indications drug "Furamag" first of all it is of course heavyinflammatory infections caused by microorganisms that are sensitive to this antibiotic. High efficacy is observed in the treatment of diseases of the urogenital system, is indispensable means "Furamag" for cystitis (chronic or acute), urethritis, pyelonephritis.
The instruction classifies the advantages of the drug “Furamag” no side effects in contrast to other nitrofurans, only in isolated cases can nausea with vomiting, neuritis, and allergic reactions be observed.
TO contraindications для приема препарата относятся особая sensitivity of the body to its components, the patient's pregnancy and the period of breastfeeding. Not recommended treatment means "Furamag" for renal failure.
If it happens overdose drug, it manifests itself asneurotoxic reactions (it is extremely rare and only in patients with diseased kidneys). In these cases, enterosorbent therapy, gastric lavage and heavy drinking are recommended.
There are a number of drugsinteraction with which is contraindicated for a number of reasons. These include "chloramphenicol", "Ristomycin", sulfonamides (inhibit hematopoiesis), nalidixic acid (causes antagonism). The drug weakens the effect of other uroantiseptics when used together, the use of acids is not recommended.
Storage of the drug "Furamag" is recommended in a dark cool place at a maximum temperature of 25 ° C.
