Among antibacterial drugs for many yearsone of the most popular is "Linkomycin." Analogues of the drug, which appeared later, have the same effect and are no less effective. These are narrow-spectrum antibiotics that are active against gram-positive and anaerobic bacteria. "Lincomycin" refers to the group of lincosamides. Allocated these drugs in a separate form because of the specificity of their action.
Features of lincosamides
This group of antibiotics includes"Lincomycin" and "Clindamycin" - its semisynthetic analogue. They have a special mechanism of action on bacteria. In general, these are preparations that affect protein synthesis in microorganism cells, which prevents their reproduction. This is the so-called bacteriostatic effect. But in high concentrations bactericidal effect of the drug "Lincomycin". Analogues of it have the same properties.
They are effective against gram-positive cocci:streptococci, staphylococci, pneumococci. But gram-positive bacteria, fungi, protozoa and viruses can not destroy "Linkomycin." Analogues of it, like the drug itself, are prescribed for:
- infections of the skin, bones and joints;
- peritonitis, abscess, furunculosis;
- diseases of the pelvic organs - endometrium, adnexitis, vaginosis;
- tonsillitis, pharyngitis, pneumonia;
- scarlet fever, diphtheria;
- rozhistom inflammation, impetigo, acne.
Contraindications and side effects
"Lincomycin" and its analogues are rapidly absorbed intogastrointestinal tract and after a couple of hours are found in all tissues and body environments, including breast milk and bones. Therefore, lincosamides are contraindicated in diseases of the digestive tract, liver and kidneys, pregnancy and lactation, as well as with individual intolerance.
When using these drugs, these side effects are possible:
- abdominal pain, nausea;
- allergic reactions, rash, itching, Quincke's edema;
- fever, sore throat;
- candidiasis;
- bleeding disorder.
"Lincomycin": instructions for use
Analogs of the preparation have the same composition and methodactions. They can be purchased under several names: "Lincomycin", "Lincomycin hydrochloride", "Cilimycin", "Neloren", "Medoglitzin", "Linosin", "Lincocin". All these drugs have the same efficacy against gram-positive bacteria. Especially often they are used against streptococci, which are resistant to the effects of other antibiotics.
These drugs are produced in tablets orcapsules, most often 500 mg. Take them need a few hours before meals, since any food greatly reduces the effectiveness of the action. Usually prescribe 3-4 times the medication. Duration of treatment is 1-2 weeks. But with complex infections of the skin, soft tissues and bone system, it can be extended to 3 weeks. After all, the resistance of microorganisms to "Linkomycin", if it is produced, it is very slow.
Features of the application of "Linkomycin" and its analogues
These drugs have long been used in medicine.After all, some microorganisms are insensitive to penicillins and other groups of antibacterial drugs, in this case, "Lincomycin" is effective. Analogues in tablets are used for sepsis, postoperative complications, osteomyelitis, purulent arthritis, furunculosis, pneumonia.
For a long time used the drug in dentistry.He is more effective than other antibiotics coping with periodontitis, gingivitis, prevents the development of caries. The best analogue of "Linkomycin" in dentistry is the plaster "Diplen Denta L". It is pasted on the affected area of the gum for 6-8 hours, during which the active substances destroy the bacteria.
Only according to the doctor's prescription should take"Lincomycin". Analogues of the drug, like himself, are incompatible with many other drugs, so do not use them yourself for treatment. Contraindicated to use "Lincomycin" in conjunction with cephalosporins, aminoglycosides, muscle relaxants, barbiturates, "Theophylline" and some other drugs.
"Lincomycin" (ointment): analogues
The drug is also available for external use.As an ointment, it is used in the treatment of purulent-inflammatory skin diseases. Produced under the name "Linkomycin Akos". This ointment is effective in the treatment of pyoderma, furunculosis, phlegmon, erysipelas, acne. The drug should be applied a thin layer on the affected area 2-3 times a day. It is advisable not to use ointment, if the inflammation is complicated by a fungal infection.
To prevent wound infectionSurgical operations and dental interventions are applied "Films with lincomycin." These are special sterile wipes, soaked in antibiotic solution.
Аналогичным действием обладает лечебный гель на based clindamycin - "Dalacin." It is effective for acne. But most often the drug is used for vaginal infections. There is another remedy that contains clindomycin - it's Clindavid, which is effective against acne.
There are other antibacterial ointments that havesimilar action. They should be used if there is intolerance to lincosamides. These are Levomekol, Tetracycline ointment, Bactroban, Metronidazole and others.
The drug "Clindamycin"
This is a semi-synthetic analogue of "Linkomycin.""Clindamycin" is the second representative of the group of lincosamides. It is available in the form of capsules, granules for the preparation of a suspension and solution for injection. "Clindamycin" can be purchased under such names: "Dalatsin", "Klimitsin", "Klindafer", "Klinoksin." These are more new preparations of the group of lincosamides, devoid of some disadvantages:
- they are more active against bacteria;
- better and faster absorbed from the gastrointestinal tract;
- their effectiveness is not dependent on food intake;
- they are active against protozoa, so they are often used in the treatment of chlamydia and other vaginal infections.
But "Clindamycin" more often causes such a side effect, like pseudomembranous colitis. In addition, it is much more expensive - 130-150 rubles.
Feedback on the use of lincosamides
For many years, popularLincomycin. Its analogs are also known and also distributed. Low cost - about 40-50 rubles, effectiveness against severe infections and a small number of contraindications often make lincosamides the drugs of choice for treatment. Especially a lot of positive reviews about the use of "Lincomycin" and its analogues after tooth extraction. Patients note that the wound quickly healed, and there was no inflammation. Effectively prevents infection of this drug after fractures and soft tissue damage.
There are negative reviews about taking lincosamides.Most often note the development of side effects: diarrhea, abdominal pain, allergic rashes. But mostly it happens with individual intolerance. To prevent this, you need to drink drugs that normalize the intestinal microflora along with taking an antibiotic.
