The drug "Ceftriaxone" refers topharmacological group of cephalosporin antibiotics, has bactericidal and antibacterial properties. The drug has a wide range of action, destroys the biosynthesis of mucopeptide bacterial cell walls, inhibits transpeptidase.
The drug is made in the form of white oryellowish-orange powder for the preparation of injections in vials of 0.5, 1 and 2 grams. The substance is easily soluble in water, the color of the injection varies from yellow to amber depending on the shelf life.
The drug "Ceftriaxone": indications for use
The drug is prescribed for the treatment of infectiousmanifestations that are caused by microorganisms that are sensitive to antibiotics. The list of indications includes infections of the upper respiratory tract, lower and upper respiratory tract, any form of bronchitis, empyema, lung abscess.
Effective drug "Ceftriaxone" for pneumonia,infectious pathologies of soft tissues and skin infections, streptoderma. The antibiotic is used to treat the urogenital system, pyelonephritis, pyelitis, prostatitis, cystitis, epididymitis, gynecological infections, simple forms of gonorrhea.
The drug is used to destroy microorganisms that affect the organs of the abdominal cavity, gastrointestinal system, biliary tract.
It is necessary to use the drug "Ceftriaxone" for sinus, for the treatment of peritonitis, sepsis and bacterial septicemia, endocarditis and meningitis, osteomyelitis, syphilis, chancroid and spirochetosis.
In some cases, the injection solution is prescribed for the treatment of salmonellosis, typhoid fever, as well as for the prevention of purulent, septic complications after the surgery.
The drug "Ceftriaxone": indications for use and method of application
The antibiotic is administered intravenously and intramuscularly. For treatment, you can use only fresh solutions.
With intramuscular injection, the powder is dissolved insterile water intended for injection. To use half and 1 gram of the drug take 2 and 3.5 ml of water, respectively. Injections are injected sufficiently deep into the outer upper part of the gluteus muscle (no more than 1 g in one place). To eliminate pain, you can use a one-percent solution of the drug "Lidocaine."
For intravenous treatment, the antibiotic is dissolved in sterile water for the production of injections in a ratio of 0.5 g to 5 ml. Inject the solution into a vein slowly over a period of three to four minutes.
The drug "Ceftriaxone": indications for use and side effects
In general, the antibiotic is well tolerated by patients.However, in some cases, vomiting, nausea, diarrhea, cholestatic jaundice, hepatitis, pseudomembranous colitis may occur. When using the medication, allergies are possible, manifested in the form of pruritus and rash, eosinophilia. On the part of the urinary system, a reaction in the form of interstitial nephritis is possible, and on the side of the circulatory system, hypoprothrombinemia may be observed.
The drug "Ceftriaxone": indications for use, contraindications and overdose
The tool is not prescribed for increasedsensitivity to the drug, penicillin and other cephalosporins. The use of the drug in the first trimester of pregnancy, breastfeeding, and renal or hepatic insufficiency is unacceptable.
With long-term drug treatmentCeftriaxone using high doses may change the blood picture (thrombocytopenia, hemolytic anemia, neutropenia, leukopenia). High excess plasma concentrations of a substance cannot be reduced by peritoneal or hemodialysis, therefore, treatment in such cases is symptomatic.
