Pharmaceutical preparation "Progestogel" is used to treat mastodinia and cystic fibrosis mastopathy. It is available as a semi-transparent, colorless gel for external use.
"Prohorest". Instructions
pharmachologic effect
As the main component of this drugis progesterone. By blocking the estrogen receptors, it improves the absorption of fluid from the soft tissues. This allows you to reduce the squeezing of the milk ducts and block the prolactin receptors, thereby reducing lactopoiesis.
Progestogel gel, instructions for usewhich indicates its transdermal route of application, does not have adverse effects on the human body. Experiments showed that an hour after the application of this drug, the level of hormones in the blood remained the same.
Excretion of Progestogel 1
Progesterone and other components of the drug are 50% excreted from the human body by the kidneys and by 10% with bile.
Dosage
One application of the gel in 2, 5 g.with the help of a dispenser should be applied to the skin of the mammary glands and left for a while (until the drug is completely absorbed). This procedure is recommended to be performed twice a day during the second phase of menstruation (16-25 days). The course of treatment with this drug is carried out over three cycles of the regula. Repeated therapy is performed only according to the doctor's prescription.
Overdose of Progestogel
The instructions for use indicate that due to a sufficiently low systemic absorption of the drug, an overdose is unlikely.
Side effects of the drug "Progestogel"
When using this medicationcan be observed weak pain in the area of the mammary glands, metrorrhagia, hot flushes, decreased libido. Quite rare in the place of application occurs erythema. In some cases, swelling of the neck and lips, headache, fever, nausea.
Drug Interactions
With the simultaneous use of the gel and combined hormonal contraceptives, its effect can be greatly enhanced.
Conditions for storage of the preparation "Progestogel" (gel)
Instruction for use indicates that thisit is recommended to keep the medicinal product at a temperature not exceeding twenty five degrees. Use the drug without harm to health can be no more than three years.
Contraindications
Do not apply this pharmaceuticalmeans in the presence of nodal forms of cystic fibrosis mastopathy, genital and breast cancer, tumors of unexplained etiology, in the second and third trimesters of pregnancy. It is not recommended to use the drug with special sensitivity to its components, which are in its composition.
With renal and hepatic insufficiency,epilepsy, bronchial asthma, depression, migraine, ectopic pregnancy, hyperlipoproteinemia, a tendency to thrombosis, acute phlebitis, vaginal bleeding, arterial hypertension, porphyria and diabetes mellitus, this pharmaceutical agent should be used with extreme caution.
Special instructions when using Progestogel
Instructions for its use indicate that afterApplying the gel should avoid contact with sunlight. The drug should not be rubbed into the skin, and mammary glands should not be massaged.
The pharmaceutical agent can be used for mastodinia that has arisen in connection with the use of oral contraceptives, during puberty and during menopause.
Studies on the effect of the drug "Progestogel" on the patient's ability to drive were not conducted.
