What does elevated fibrinogen mean? The rate of fibrinogen in pregnancy

Fibrinogen is a special protein in the blood serum,which participates in the process of coagulation. If necessary (any bleeding), it breaks up into separate strands (this happens under the influence of another protein - fibrin). With the help of these threads, the blood coagulates and the bleeding stops. Reduced or elevated fibrinogen can speak about some deviations. Its norm in the blood varies in the range from 2 to 4 g / l. In some physiological processes, the rate of this indicator may increase. For example, fibrinogen is elevated in pregnancy to 6 g / l.

What else can evidence increased fibrinogen? A sharp increase in this indicator in the blood can speak of the following pathological conditions:

• pneumonia;
• myocardial infarction;
• stroke;
• various oncological diseases;
• acute infections and inflammatory processes;
• hypothyroidism;
• amyloidosis.

In any case, the exact reason for the increasefibrinogen in the blood will set the doctor. To clarify the diagnosis will need some more surveys. Also, elevated fibrinogen can be observed after recent injuries, burns, surgery and as a result of taking certain drugs. For example, this figure is increased when taking estrogens.

Elevated fibrinogen during pregnancy isnorm. Pregnancy is a physiological process, during which the entire body of a woman is reconstructed, thus preparing her for the upcoming birth. The increase in fibrinogen in this case occurs gradually. In the first two trimesters of pregnancy, the amount of fibrinogen should not exceed 4 g / l. The maximum increase in this indicator occurs at the end of the third trimester, almost before childbirth. If fibrinogen in the blood is raised precisely in this period, then this is the norm. In other cases, we must look for a different reason. It can be any infectious disease or acute inflammatory process, and also it can point to the begun process of death of tissues. In these cases, you should urgently go to the doctor. Such situations can have very deplorable consequences for both the future mother and the unborn child. Most likely, such a pregnant woman will be offered hospitalization, and all further examinations she will already be in the hospital, as finding her home can endanger the life of the baby and the future mother. Also, a sharp decline in this indicator can be indicative of pathology. This could mean:

• insufficient amount of vitamin B12 or C;
• DIC-syndrome;
• severe toxicosis in late pregnancy.

Norms of fibrinogen in the blood:

Newborns	1.25-3 g / l
Adults	2-4 g / l
Pregnancy 3rd trimester	up to 6 g / l

Blood for fibrinogen is surrendered from the vein in the morningon an empty stomach, as a last resort, from the moment of reception of food to delivery of the given analysis it is necessary to sustain not less than two hours. Blood is taken into a specially treated test tube with the addition of a reagent. After this, several times it is carefully turned over to better mix the reagent with the blood. Only in this case it is possible to obtain a reliable analysis, and it must be done no later than two hours after the blood donation.