A person is endowed with a certain blood group.when it is in the womb. This is a genetically transmitted trait, like skin color, an eye that remains for life. But still there are opinions that the change in blood type is quite possible. Let's try to figure out whether the blood group can change, or is it just the result of an error when performing an analysis?
Blood type determination
Widespread in the world hasclassification according to the ABO system, within which there are four blood groups established by analysis. To carry it out, four serums with antibodies to which blood is added are needed. The laboratory assistant monitors the reaction of red blood cells and the process of their connection. It is based on the results of agglutination is determined by group affiliation.
Группы крови системы АВО являются основными и used when transfusing. Associated antibodies A and B (immunoglobulins) are most often formed in the first years of life as a result of susceptibility to substances surrounding a person (food, viruses, bacteria).
Blood is a sign that a person is endowed with.at birth, and having a specific composition of agglutinogens and agglutinins, genetically encoded. In all respects, it would seem impossible to talk about changing the blood group. So can blood type change? We will understand. Still, such cases can occur for a number of specific reasons, which we further list.
Error in the analysis
Possible erroneous analysis onestablishing the patient's blood group. Despite the simplicity of this procedure, the likelihood of an incorrect result can never be ruled out, so at some point in life a person may think that he has a different blood type.
Pregnancy
Pregnancy can also affect the outcome.During this period, the production of red blood cells increases, and the concentration of agglutinogens decreases so much that the red blood cells that contain them do not fuse. Perhaps because of this, many wonder if the blood group changes in life.
Diseases
There are diseases during the course ofwhich red blood cell composition may also increase, as was the case in the previous case, and the blood group may change. In addition, certain pathogenic microbes and bacteria emit enzymes that change the composition of agglutinogens of type A so that they begin to resemble agglutinogens of type B.
Анализ крови в данном случае покажет вторую group instead of the third, but at the same time transfusion of group B is in any case impossible, since it will cause incompatible reactions. Thus, the change is temporary. So, to reduce the content of antigens can thalassemia (Cooley's disease). Cancers can also contribute to these changes.
Thus, under certain conditionstest results may temporarily be different, but a change of group membership is basically impossible. Therefore, the answer to the question of whether the blood type can change will be negative.
Rh factor
In medicine it is categorically stated thatRhesus factor and blood type are constant indicators, inherited properties, obtained even at conception and remaining to death. But sometimes events occur that cannot be explained by a rational method. Opinions about the possibility of changing the blood group and rhesus are also found. Find out whether the blood group and the Rh factor.
Rh factor - a trait that has a genetic origin, and its change in natural conditions is not feasible. To determine it, you need to check for the presence of Rh antigen on red blood cells. This protein is found in 85% of humanity, and the rhesus is positive. The rest, respectively, have a negative figure.
But there are antigens in the Rh system, whichare not so immunogenic. In some people with positive rhesus, the ability to produce opposite antibodies is detected, and the expression of the standard Rh antigen is significantly reduced. In this case, positive patients are classified as negative. For example, if donated blood reaches a patient, an immune conflict may occur.
To determine the rhesus need in the planning processpregnancy in order to promptly detect possible immunological conflict between the fetus and the mother, as a result of which the child may develop a hemolytic disease.
So does blood type change during life? There are exceptions to the rule. About this further.
Unique case
A case of a change in the Rh factor was once recorded by Australian doctors in a girl after a liver transplant. Then she changed all the properties of the immune system.
During transplantation, this phenomenon is verywelcome, because most often the body is trying to reject a new organ, which represents a threat to the patient's life. To prevent such a development of events, the patient is prescribed a long-term administration of drugs that suppress the functioning of the immune system. To some extent, this is a non-standard answer to the question of whether the blood group of women is changing.
Custom script
The case of a fifteen-year-old girl went wrongstandard script. When the transplantation was performed, the doctors did all the usual procedures, but over time the patient developed a disease that rebuilt her immune system. After recovery, an analysis was carried out, which showed that the blood in some incomprehensible way became positive, although it was negative before the liver transplant. As a result, even the testimony of immunity became the same as that of the donor.
Doctors explain this case by postponingstem cell donor organ in the bone marrow of the girl. An additional basis could serve her young age, because of which there was a small amount of leukocytes in the blood. However, such a case is still a single one; more such phenomena have not been fixed.
Therefore, when asking whether a person’s blood type is changing, one must boldly answer: “No.” But the Rh factor may change.
Advanced Rhesus Tutorial
Researchers at the brazilian institute inSão João de Meriti, after many tests carried out among patients undergoing spleen and liver transplantation, concluded that the protein on red blood cells could change if certain conditions coincide.
Studies show that almost 12% of patients after transplantation are at risk of changing the sign of the Rh factor, although the blood group is preserved.
Dr. Itar Minas claims thatThe functioning of the immune system after organ transplantation is significantly restructured, especially those that synthesize erythrocyte antigen. He explains this by the fact that during the engraftment of an organ, the stem cells are able to take over some of the blood-forming functions of the bone marrow, and as a result, the polarity of the rhesus can change.
Значимыми являются также возраст донора и recipient. Young people have more opportunities for antigen restructuring than older ones. This group of scientists believes that the content of information on protein determinants, which are located in chromosomal alleles and loci (the exact number has not yet been established), also has an effect. It is assumed that some of them may allow the possibility of changing the Rh factor.
So we figured out the question of whether a blood group can change during life.
