Enzyme preparation "Pancreatin". Analogues

Occasional pain and heaviness in the abdomenalmost every person. This usually occurs after ingestion of fatty foods, overeating, and disorders of the gastrointestinal tract. The digestive system contains many enzymes that break down proteins, fats and carbohydrates. Then the crushed substances enter the small intestine. There they are absorbed and spread through the circulatory system of the body. Sometimes the splitting process is disturbed, and the main elements of the food reach the intestine in unchanged form. This leads to impaired absorption, as well as dyspeptic disorders (diarrhea, delayed stool). In some cases, the body's own enzymes do not have time to perform their function in the required volume, which is expressed in the severity of the abdomen, painful sensations in the epigastric region, right and left hypochondrium. Most often this is due to malnutrition. In such cases, the drug Pancreatin, whose analogues are known to many, helps to remove unpleasant feelings.

Mechanism of action of the drug

In order to improve the digestive process,It is necessary to fill the lack of enzymes. The drug "Pancreatin" acts according to this principle. It consists of a number of enzymes of the pancreas of pigs and cattle, which in their composition are suitable for the human digestive tract. The main active ingredients of the drug:

1. Lipase - for the breakdown of fats.
2. Pancreatic amylase - crushes food carbohydrates.
3. Proteases, among which there is chymotrypsin and trypsin - these enzymes affect food proteins.

Если врач выписал данный препарат, но его нет в the moment is available, it is easy to replace the drug "Pancreatin", which has analogues in any pharmacy. These include the following medicinal substances: "Mezim", "Pankreazim", "Creon", "Panzinorm", "Festal", "Gastinorm forte", etc.

Indications for use

Enzyme preparations are used when impairedpancreatic secretion. The causes may be different, most often it is a disease of the gastrointestinal tract. Indications are: pancreatitis of various etiologies, including alcohol, cystic fibrosis - a disease associated with impaired protein metabolism. In addition, when removing the gland, to compensate for the enzyme loss, use the drug "Pancreatin". Analogues of the drug are prescribed for the same violations. In addition, these drugs are effective in dyspeptic disorders, flatulence, diarrhea, cholecystitis, bile duct disease, insufficiency of the small intestine and stomach during their removal.

Differences between analogs of the drug "Pancreatin"

All listed medicines havethe same basis and active ingredient - enzymes of the pancreas of animals. Therefore, when buying these funds, patients often ask questions: "Pancreatin" or "Mezim", which is better? Why is there a difference in price and does it affect efficiency?

In fact, the differences in analogs are small:they consist in the dosage of basic enzymes, the presence or absence of bile and hemicellulose in the composition of the drug. For example, the medication Mezim-forte contains 3500 or 10000 U of lipase, and does not have additional components. In turn, the drug "Festal" contains more bile and hemicellulose. If you choose that it is better to buy the drug "Creon" or "Pancreatin", then pay attention to the degree of lack of enzymes, since the first has a higher concentration of lipase, so it can be used in smaller quantities.

Contraindications to the use of the drug "Pancreatin" and its analogues

All enzyme preparations, regardless ofThe concentration of the active substance should not be taken in newborns and children under two years. This is due to the fact that they have not yet fully developed the function of the digestive tract. Also, in case of hypersensitivity to pork and beef, intestinal obstruction and exacerbations of chronic diseases, the drug Pancreatin cannot be used. Analogs also have these contraindications. It should be remembered that medications are used only for chronic inflammation of the pancreas. Acute pancreatitis is a contraindication to the use of enzyme preparations, as they can cause an erased course of the disease and worsen its prognosis.

Side effects of the drug and its analogues

Medicines that have an enzyme in their compositionpancreatin, can cause local and general effects on the body. The general effects of the use of drugs include hypersensitivity reactions, positive symptoms of peritoneal irritation, as well as a violation of the absorption of folic acid. If you use drugs "Pancreatin" or "Mezim", then there may be local side effects, that is, disorders in the digestive system. These include: nausea, vomiting, diarrhea or constipation, discomfort in the epigastric region. In the treatment of cystic fibrosis may be observed intestinal obstruction.

Interaction with other medicines

При одновременном применении антацидов (снижают the acidity of the stomach) the effect of the drug "Pancreatin" and its analogues weakens. If a patient takes iron or folic acid, then enzyme medications will help slow down or interfere with their absorption in the intestine.

Medicinal substances should be applied afterconsultation with your doctor. Medication "Pancreatin" can be used for minor digestive disorders (severity after fatty food), analogues "Creon" and "Mezim" prescribed for more severe processes (chronic diseases, removal of the pancreas).