Is the drug "Microzyme" effective - a drugPatient reviews about which you can find in this article? Today we will tell about it. Also from the material you will definitely learn about the diseases for which such a drug is prescribed, how much it costs, whether it has side effects, analogues and contraindications.
Composition, form
What substances does Mikrozim include?(medicine)? Reviews of experts indicate that the active element of this drug is pancreatin. As auxiliary substances, this agent contains Eudragit, triethyl citrate, simethicone, talc, gelatin, water, sodium lauryl sulfate, methyl para-hydroxybenzoate, dyes and propyl paraben.
В какой форме можно приобрести ферментные drugs of this type? "Micrazim" is sold in capsule form. They have a transparent body and a brown cover. Inside they contain cylindrical or spherical pellets of light brown or brown color. In this case, the granules of the drug have a characteristic odor.
For the treatment can be recommended capsules 10 000 IU and 25 000 IU.
Pharmacological action of the enzyme preparation
What properties has consideredmedicament? It is a tool that belongs to the latest generation of enzyme preparations. It contains such an active ingredient as pancreatin. This is an enzyme that is actively involved in the processes of digestion.
As you know, the pancreatin includes suchsubstances like lipase, amylase and protease. They are pancreatic enzymes and contribute to the process of assimilation of fats, carbohydrates and proteins.
Gelatin capsules contain pancreatin granules, which resemble mini-microspheres that are resistant to gastric juice. This effect is provided by a special coating.
Thus, enzyme preparations of this type are directly involved in digestion, passing through the intestines. At the same time, they have no effect on the stomach.
Pharmacokinetic features
After what time does “Microzim” start to act?(medicine)? Testimonials say that enzymes begin to be released in the small intestine. After that, they contribute to the digestion of food, as well as the normalization of digestive processes.
После принятия капсулы внутрь она на протяжении it dissolves in the stomach for several minutes and then enters the intestine where mini-microspheres are released. The effect of the drug occurs in about 40 minutes. At the same time only its local impact is noted. In the intestine, the drug is not absorbed. The output of the substance is carried out with feces.
Indications for use
The drug "Microzyme" is recommended to take in the following cases:
- For symptomatic treatment of process disordersdigestion (for example, in gastritis with low acidity, occurring in a chronic form, functional dyspepsia, diseases of the liver and biliary tract, diseases of the small or large intestine, in the presence of which their evacuation function is impaired, as well as after partial removal of the intestine, gall bladder or stomach) .
- As a substitution treatment for people withpancreatic insufficiency (for example, in cystic fibrosis, chronic inflammation of the pancreas, pancreatic tumors, as well as after its removal).
- With a comprehensive preparation for x-ray examination or ultrasound of the abdominal cavity.
- To ensure the processes of digestion duringnormal functioning of the digestive tract (for example, with overeating, eating very fatty and high-calorie foods, chewing disorders, prolonged immobilization, etc.).
Contraindications for use
Under what conditions can not take "Microzim" (medicine)? Reviews of doctors speak about the following prohibitions:
- patient intolerance to pancreatin or its components;
- exacerbations of chronic changes in the pancreas;
- inflammation in the pancreas, especially occurring in the acute form.
Drug "Microzim": instructions
According to the instructions attached to the drug, 10000 units of pancreatin must be taken after eating or in the process of eating. In this case, drink the medicine preferably with a large amount of liquid. The capsule is not recommended to chew or divide. If the patient cannot take it entirely, then its contents must be mixed with water or food. The resulting mixture is required to swallow without chewing.
Маленьким пациентам до 4 лет с диагнозом "Cystic fibrosis" is indicated to receive 1000 Units of lipase per kilogram of body weight. After four years of age, babies should receive about 500 U of lipase per kilogram of weight. The maximum allowable dosage is 10,000 U / kg per day.
With steatorrhea and diarrhea, each meal is recommended to take 25,000 units of the drug. The highest permissible dose is 35 000 Units.
Signs of an overdose
What symptoms occur when taking elevateddoses of medicine "Microzim"? The analogue of this drug and the drug itself can cause quite severe constipation, as well as hyperuricemia and hyperuricuria. With such signs, it is necessary to cancel the treatment, as well as use a lot of fluids and to carry out symptomatic therapy.
Adverse Events
In most cases, the drug "Mikrozim"tolerated by patients quite well. However, in rare cases, it can cause some side effects. In this case, the medication should be abolished or the dosage adjusted.
Most often, patients have the following side effects:
- constipation;
- skin allergy (rash, urticaria);
- diarrhea;
- nausea and vomiting;
- epigastric discomfort;
- elevated uric acid in blood and urine tests.
Cases of narrowing of the intestinal lumen in patients diagnosed with cystic fibrosis were also recorded.
Drug Interactions
With the combination of the drug "Microzyme" with othermedications should be borne in mind that against this background the absorption of iron and folic acid may decrease. The bioavailability of the drug is reduced if it is simultaneously taken with antacids, which contain magnesium hydroxide or calcium carbonate.
special instructions
With long-term admission should be carefully monitored the patient's health.
A decrease in pharmacologicalefficacy of the drug in case of helminthic invasions, dysbiosis, duodenostasis and acidification of the intestinal contents. Also, the effectiveness of the drug is reduced if it is taken after the expiration date.
If you store the drug at a high temperature, then the activity of its mini-microspheres rather quickly decreases.
The ability of a person to focus, drive a car or work with complex mechanisms does not affect the use of the drug.
During therapy, the capsules should always drink plenty of water. However, it is not recommended to use alkaline water.
Medicine "Microzim": price, analogues
Analogues of the drug on the active substanceThe following drugs are used: Likreaz, Pankrenorm, Gastenorm, Pankreal, Creon, Panzinorm, Enzistal, Pancreatin, Pankrelipaz, Panzim and others. But it is possible to replace the prescribed medication with a generic drug only after consulting with your doctor.
The cost of the drug is not very high. On average, the price for 20 capsules is 150-400 rubles and depends on the dosage.
Gestation period, baby age, breastfeeding
For the treatment of children, the drug is prescribed onlypediatricians. During pregnancy and during breastfeeding, the drug can be taken only if the benefits of it outweigh the likely risk.
It should also be noted that today there is no data on the penetration of pancreatin into breast milk.
Enzyme Medication Patient Reviews
Most reviews of the drug "Microzim" arepositive character. Patients observe a marked improvement in their condition with regular use of this medication during meals. In this case, they note that it not only helps with diseases of the digestive system and pancreas, but also allows you to overcome all the unpleasant symptoms that occur during overeating.
However, reviews of doctors indicate that this medicine should be taken only according to the indications. Otherwise, its uncontrolled reception may not give the expected effect.
