Is Belara medication effective?Reviews of doctors (pros, cons) will be presented below. You will also learn about the form in which this drug is made, what components it contains, whether it has contraindications and side effects.
Description, composition, shape, packaging
The drug "Belara" goes on sale in the form ofround biconvex light pink tablets with a white core. It contains active ingredients such as chlormadinone acetate and ethinyl estradiol. It also contains additional ingredients in the form of lactose monohydrate, povidone, cornstarch and magnesium stearate.
As for the pink film shell, it consists of titanium dioxide, talc, hypromellose, lactose monohydrate, macrogol 6000, propylene glycol and a dye of red iron oxide.
In the sale of the medium in question comes in blisters, which are contained in a cardboard box.
Pharmacodynamics
What is the drug "Belara"? Reviews of doctors (pluses, minuses of the drug will be presented later) state that this is a combined contraceptive device intended for oral administration.
Prolonged use of tablets reducessecretion of luteinizing and follicle-stimulating hormones and, as a result, inhibits the process of ovulation. Also, this drug contributes to the proliferation and secretory transformation of the endometrium. Such an impact prevents the fertilized egg from fixing.
When you receive this medication increases the viscosity of mucous secretions from the cervix. Due to this, male reproductive cells with difficulty pass through the female genital organs.
Chlormadinone acetate included in this drugis a gestagen, which has anti-androgenic properties. It is able to compete with androgens in specific receptors and thereby weaken their effect.
The likely onset of pregnancy for the year varies between 0.29-0.69%, and depends on strict adherence to the dosing regimen and medication.
Pharmacokinetics
Tablets "Belara" contain two active substances. Their kinetic indicators vary markedly:
- Chlormadinone Acetate quite quickly and completely absorbed from the digestive tract. Its greatest concentration in the blood is observed in an hour and a half. About 95% of the substance is bound to plasma proteins (mainly albumin).
During the transformation of a component, several metabolites are formed (3-alpha- and 3-beta-hydroxy-chlormadinone acetate).
The elimination half-life of this element is 33 hours. Chlormadinone acetate, as well as its metabolites are excreted in equal quantities with urine and feces.
- Ethinyl Estradiol also quickly and completely absorbed from the intestines. Its highest plasma concentration is reached after 90 minutes. The absolute bioavailability of this substance is 40%.
Approximately 98% of ethinyl estradiol is bound toblood proteins. It is transformed by hydroxylation of the aromatic ring. The main derivative of this substance is 2-hydroxy-ethinyl estradiol.
The half-life of the considered component is 13 hours. It is derived from the feces and through the kidneys in the ratio of 3: 2.
To completely block ovulation, chlormadinone acetate must be taken in an amount of 1.7 mg each day. The dosage for a full cycle is about 25 mg.
Indications for use
The tablets "Belara" are intended only for the fairer sex. They are required for oral contraception.
Contraindications
Under what conditions can you not take Belara medication? Reviews of doctors (pros, cons of this tool should take into account all women) report that this drug can not be used for:
- thrombosis and thromboembolism (pulmonary embolism, myocardial infarction, venous thrombosis, cerebrovascular changes);
- planned surgical intervention (one month before it), as well as during the period of immobilization;
- uncontrolled arterial hypertension;
- initial signs of thrombosis or thrombophlebitis, as well as with symptoms of embolism (including temporary ischemic attacks);
- acute or chronic severe liver damage;
- uncontrolled diabetes mellitus;
- itching of the whole body, cholestasis;
- susceptibility to the appearance of arterial and venous thrombosis;
- severe epigastric pain, hepatomegaly, or signs of intraperitoneal bleeding;
- liver tumors;
- migraine attacks;
- Rotor or Dubin-Johnson syndrome, as well as slowing the flow of bile;
- movement disorders;
- acute sensory impairment;
- porphyrias;
- hormone-dependent malignant tumors or suspicion of them;
- severe depression;
- pancreatitis;
- cryptogenic amenorrhea;
- pronounced changes in lipid metabolism;
- during lactation;
- increasing the frequency of epilepsy attacks;
- pregnancy;
- complicated course of otosclerosis, including during previous pregnancies;
- addiction to smoking (patients from 35 years);
- endometrial hyperplasia;
- lactose intolerance, lactase deficiency and glucose-galactose malabsorption;
- vaginal bleeding of unknown origin;
- the presence of multiple risk factors for venous or arterial thrombosis;
- sensitization to substances of the drug.
How to drink the contraceptive pills "Belara"?
According to the instructions, birth control pillsshould be taken orally, without chewing and squeezed with a small amount of water. How should receive? "Belara" must be taken daily at the same time (in the evening).
The duration of the drug is 21 days. Next, it must be interrupted for a week. About 2-4 days after the last pill, menstrual bleeding is observed.
After seven days, you are required to start taking the drug from another pack, regardless of whether the bleeding has stopped or not.
The first pill should be used on day 1.physiological cycle (that is, on the first day of the next menstruation). Only in this case contraception begins its action and lasts even during a week break.
However, the first tablet can be taken for 2-5 days of the menstrual cycle. In this case, during the first 7 days, you should use barrier methods of contraception.
If menstruation began more than 5 days ago, then it is necessary to wait for the start of the next one, and only then proceed to the cycle of taking pills.
Side effects
Now you know how to drink birth control pills. It should also be borne in mind that taking this drug can cause the following side reactions:
- nervousness, irritability, depressed mood, weakening of libido;
- increased appetite, changes in blood fat;
- hypersensitivity to the drug;
- contact lens intolerance, visual disturbances, conjunctivitis, tinnitus, hearing loss;
- dizziness, migraine pain;
- venous thrombosis, increased pressure, collapse, arterial hypotension, varicose veins, arterial hypertension;
- flatulence, abdominal pain, nausea, diarrhea, vomiting;
- hyperhidrosis, acne, erythema, chloasma, urticaria, hair loss, pigmentation disorders, eczema;
- lumbodynia, feeling of heaviness, muscle disorders;
- vaginal candidiasis, dysmenorrhea, vulvovaginitis, increased vaginal discharge, premenstrual syndrome, amenorrhea, breast fibroadenoma, lower abdominal pain.
Drug Interactions
Can Belara contraceptives be combined with other drugs? Using these tablets with others may weaken their effect. These overwhelming drugs include:
- substances that activate microsomal liver enzymes;
- intestinal motility enhancers;
- some antibiotics.
After the “Belara” and the receipt of these funds should use additional methods of contraception.
Price and analogy
Analogues of the drug in question arethe following: "Vidora", "Dyla", "Jess", "Difenda", "Zhanin", "Lindinet 20", "Logest", "Mersilon", "Milanda", "Model Tin", "Novinet", "Silest , Femoden, Yarina Plus.
As for the price, it directly depends on the number of tablets per pack. The average cost of the drug "Belara" is 490-530 rubles (21 pcs.).
"Belara": reviews of doctors (pros, cons)
Согласно специалистам, препарат «Белара» established itself as a very reliable means of contraception. With its proper reception, unwanted pregnancy is excluded. However, this drug has negative reviews. Doctors report that it can cause a large number of side effects. This medication promotes weight gain and is also very harmful to the skin. Moreover, he has an impressive list of contraindications.
