The medicine "Arbidol" is an antiviral andimmunomodulating medication, inducer of interferon synthesis. The therapeutic effect of this drug in viral infections is to reduce the manifestations of general intoxication and clinic, reducing the duration of the disease.
Form of release of the drug "Arbidol", composition
Tablets with a coat, white or slightlycream color shade, have a biconvex shape. 1 tablet contains active ingredient - multicomponent ethyl ester of carboxylic acid - 100 mg and additional ingredients in the composition: starch of potato, methylcellulose, aerosil, calcium stearate, sugar, magnesium carbonate core, polyvinylpyrrolidone, flour, talc, titanium dioxide, pigment, beeswax.
Pharmacological action of Arbidol
The composition of the drug causes itantiviral activity consisting in immunomodulating and anti-influenza action, specific suppression of influenza viruses from group A and B. The antiviral effect of the drug Arbidol, the description given in the instruction, explains its interferon-inducing property; stimulate the humoral and cellular responses of immunity, as well as the phagocytic function of macrophages.
The composition of ingredients included in the medicine "Arbidol" is capable of:
- not to give a course to the development of post-influenza complications;
- prevent exacerbations of chronic diseases;
- normalize the body's immunological status.
Antiviral activity is due to counteracting the fusion of the viral envelope with cell membranes, so that the virus does not become infected with the cell.
Due to the fact that included in the drug "Arbidol"the composition of the ingredients helps to reduce the level of intoxication and intensity of catarrhal symptoms, shorten the duration of the fever and, in general, the total time of the disease, this drug is very effective in influenza. The drug is a low-toxic agent. There are no known negative effects of Arbidol on body systems, when taken in therapeutic doses.
Absorption of the preparation and distribution in the body
After ingestion, rapid absorption of the drug from the gastrointestinal tract occurs. After that, the distribution of the drug across all systems of the body.
Metabolism of the drug "Arbidol" and its excretion
The drug is metabolized by the liver.T1 / 2 is 17-20 hours. About 40% is excreted from the body in its original form, mainly in the bile (38.9%) and in a small volume - through the kidneys (0.12%). In the first day there is a withdrawal from the body of 90% of the dose received.
Indications
Applied for prevention and treatment in children and adults: influenza A and B, in addition, SARS, incl. with complications in the form of bronchitis and pneumonia; with secondary immunodeficiency states.
In complex therapy for chronic bronchitis,pneumonia, and also when there is a recurrent herpetic infection; for the prevention of postoperative complications of an infectious nature and normalization of the immune system in adults.
Medication "Arbidol" - instruction
Tablets are taken orally, before meals.
The drug is given for the prevention of influenza and ARVI in doses from 50 mg to 200 mg / day once a day for one and a half to two weeks.
The therapeutic dose (daily) is higher than the prophylactic dosefour times. But, in this case, not just a single dose increases, but the number of medications, i.e. the same dose of the drug is given more than once, but four times a day for five days. Then a single dose is given once / ned. for 3-4 weeks.
The amount of a single dose is determined by agefor children under 6 years of age, it is minimal (50 mg), for children up to 12 years, the dose is higher - 100 mg and for children over 12 years and for adults, the maximum dose is 200 mg.
Side effects
Perhaps the manifestation of allergic reactions.
Contraindications
Not allowed for hypersensitivity; children under 3 years.
Drug Interactions
When used with other medicinal products, no negative effects were noted.
