The drug lysobact is supplied in round tablets for resorption. Tablets are white or white with a slight shade of cream or yellow, on one side there is a dividing risk.
Composition
Active substances:
- pyridoxine hydrochloride - 10 mg (in 1 table);
- lysozyme hydrochloride - 20 mg (in 1 table).
Excipients:
- the tragic;
- magnesium stearate;
- vanillin;
- lactose monohydrate;
- saccharin sodium.
Pharmacological action of the drug lysobakt
The instruction says that the lysobact is a localantiseptic and antimicrobial drug, which is used in dentistry and ENT-practice. In addition, it has a slight analgesic effect, which plays, although not very pronounced, but a palpable role in the use of this drug in dental diseases.
One of the active substances is lysozyme, whichis a protein enzyme, is also an antiseptic, and besides it has strong antiviral and antimycotic activity. In addition, lysozyme has antibacterial activity against gram-negative and gram-positive bacteria.
The second active substance - pyridoxine -significantly enhances the regeneration of the oral mucosa. Pyridoxine in no way can affect the pharmacological characteristics and properties of the second component of the drug - lysozyme.
Pharmacokinetics
Immediately after application of the lysobacte is excellentAbsorbed into the blood from the digestive tract, reaching its maximum concentration within an hour. The components of the drug are separated in the body so that the highest concentration of lysozyme accumulates in the mucous membranes, and pyridoxine accumulates in the muscles. Pyridoxine can pass through the placental barrier and stand out when lactated with milk.
After the biotransformation of the active substances of the drugstore has been performed, lysozyme is excreted in the larger part with urine, as well as pyridoxine.
Indications for the use of the drug lysobakt
The instruction says that the drug lizobakt is intended for the treatment and prevention of infectious diseases that occur on the mucous membranes of the gums, larynx, mouth. It:
- stomatitis;
- gingivitis;
- catarrhal phenomena of the respiratory tract;
- herpes of the oral cavity;
- erosion of the mouth of various etiologies.
The drug can be used as in pregnancy,and at thoracal feeding of the child. But it is necessary to understand that pyridoxine can be excreted with milk, so when lactation it is recommended to apply the drug only after a medical consultation.
Side effects of the drug lysobakt
The instruction says that scientific research,which were conducted by independent companies, did not reveal any serious side effects after taking this drug. But in rare cases, small allergic reactions can occur to individual components of the drug, for example, to auxiliary substances.
Drug Interactions
Noticeable potentiation of the effect when combining the lysobacter and other antibacterial drugs, including penicillin, nitrofurantoin, chloramphenicol.
When using levodopa and lysobact, a decrease in the anti-parkinsonian effect of levodopa is simultaneously noticeable.
Effects of most types of diuretic drugs are potentiated if they are taken with the lysobacter. This is due to the peculiarity of pharmacological properties of the drug lysobact.
The instruction says that it is not recommendeduse together with lysobacter immunosuppressors, pyrazinamide, penicillamine, isoniazid, estrogen and estrogen-containing contraceptives, because all these drugs are pyridoxine antagonists and increase its renal secretion.
