The drug "Deprenorm MB" is amodified release medicament. The active component is trimetazidine dihydrochloride. The drug "Deprenorm" instructions for use refers to the category of antianginal drugs that improve myocardial metabolism. The drug has an antihypoxic property.
The drug directly enhances the activity andmetabolism of cardiomyocytes and neurons in the brain. Due to rationalization of oxygen consumption, increase of energy potential, activation of oxidative decarboxylation, cytoprotective action is carried out. Characterizing the drug "Deprenorm", the instruction indicates its properties to maintain normal contractility in the myocardium, prevent intracellular depletion of creatine phosphate and ATP. Under the action of a medicament under conditions of acidosis, the state of membrane ion channels is normalized, the level of potassium ions inside the cell is normalized. The drug prevents the accumulation of sodium and calcium in cardiomyocytes. The drug "Deprenorm" (instructions for use contains such data) reduces the level of phosphates, reduces acidosis inside cells, prevents the damaging activity of free radicals, ensures the integrity of cell membranes. In addition, the drug helps to increase the duration of the electrical potential.
Как отмечают специалисты, при применении medication with angina reduces the frequency of seizures and reduces the need for nitrates. Two weeks after the start of therapy, exercise tolerance increases, and pressure drops (arterial pressure) decrease. The drug "Deprenorm" (reviews of many patients indicate this) contributes to improving hearing, reducing the noise in the ears. In addition, dizziness decreases. On the background of vascular pathologies of the eyes there is an improvement in the functional state of the retina.
Drug "Deprenorm" instructions for userecommends for chorioretinal vascular disorders, cochlear-vestibular disorders of ischemic origin (hearing impairment, tinnitus). The drug is indicated in dizziness of the vascular nature, as well as to prevent attacks of angina (in combination with other drugs).
Medication "Depenorm" instructions for usedoes not admit to prescription for renal failure, expressed disorders of the liver, pregnancy. Contraindications include individual intolerance, childhood (up to eighteen years), breastfeeding.
The drug is taken orally.Dosage - seventy milligrams (two tablets), divided into two doses. The duration of treatment is set for each patient individually. Tablets are recommended to be taken with food.
The medicine "Deprenorm" can cause vomiting,nausea, gastralgia and other disorders of the gastrointestinal tract. In some cases, itchy skin, palpitations, headache can occur. As practice shows, and numerous testimonials from patients indicate that these adverse reactions rarely occur.
The drug is not intended to eliminate attacks of angina. If you have or increase seizures, you should consult a doctor. Probably, in this case, adjustment of the treatment regimen will be required.
The study did not reveal the effect of the drug on the ability to work with equipment, machinery or driving a vehicle.
Shelf life means "Deprenorm" two years. Do not take medication after the specified time.
Before taking the medicine "Deprenorm" you should consult with your doctor.
