As a rule, the medicine "Ranitidine" is produced inin the form of food-coated tablets, weighing 150 or 300 milligrams. Active ingredient - ranitidine, is present in the product in the form of hydrochloride.
Pharmacological properties of the drug "Ranitidine",The instruction is described as follows. The drug acts as an active suppressant against the H2-receptors of the cells of the gastrointestinal tract. It is able to reduce the secretion of hydrochloric acid, which occurs due to the action of baroreceptors, as well as food overload, increased hormonal activity and the action of such biogenic stimulants, such as gastrin and histamine.
Ranitidine hydrochloride has the abilityreduce the amount of gastric juice, as well as reduce the concentration of hydrochloric acid in it. The drug has the ability to raise the pH in the stomach, and this, in turn, helps to reduce pepsin. If you take the drug in the recommended and therapeutically reasonable doses, ranitidine hydrochloride does not affect the content of prolactin. It is also able to inhibit microsomal enzymes, and the duration of the active substance is 12 hours after a single dose of the recommended dose.
The drug "Ranitidine", the instruction recommends using in case of the following diseases:
- for the treatment of gastric ulcers and its prevention;
- duodenal ulcers;
- Zollinger-Ellison syndrome.
The drug is effective in the treatment of symptomatic and stressful ulcers, used in combination for the prevention and recovery in the postoperative period.
When using the drug "Ranitidine" instructionwarns of possible contraindications. For example, it states that the drug should not be used during pregnancy, for the treatment of children under 14 years of age, and also in cases where the patient has hypersensitivity to ranitidine hydrochloride.
With caution it is necessary to apply the drug in the presence of the patient's renal or liver failure.
The instruction recommends taking Ranitidine tablets without chewing, regardless of the meal time.
Dosage and duration of the drugdetermined by the nature and severity of the disease. So, in case of exacerbation of duodenal ulcers or stomach, both adults and children over the age of fourteen years, it is recommended to appoint either 150 milligrams (in two doses per day), or 300 milligrams per night in one session. According to the recommendation of the doctor, the dose may increase and amount to 450 mg. For prophylactic purposes, in relation to these diseases, the medicine is used 150 mg once, at bedtime.
In the treatment of Zollinger-Ellison syndrome,the drug is prescribed three times a day in the initial stage of treatment (150 mg each), and then the daily dose can be increased to 600-900 mg, depending on the patient's condition.
For the healing of ulcers, the drug is used twice a day at 150 mg, it provides healing for about a month.
When using the drug underthe name "Ranitidine", the instruction specifies the possibility of side effects, but they occur quite rarely. Patients may experience headaches, fatigue, and skin rashes. Cases of hair loss are very rare.
Particular caution must be exercised in patients taking the drug and who have dysfunctional disorders of the liver or kidneys.
If, after all, side effects begin to occur while taking the medicine, the prescription is canceled, and this should be done by gradually reducing the dosage.
The effectiveness of the drug in its prophylactic use is higher in spring and autumn.
The drug "Ranitidine" is included in the list of vital, which is approved by the Government of the Russian Federation, therefore its implementation in the pharmacy chain at special, lower prices.
