“Vidaza” is an antimetabolite produced in the form oflyophilisate (special powder) for suspension or already in the form of a prepared suspension for subcutaneous administration. The active ingredient of the drug called - azacytidine, entering the body, displaces the enzymes responsible for metabolic processes in cancer cells, and thereby stops their growth and disrupts viability.
Indications
The drug "Vaidaza", instructions for use of which will be proposed later in our article, is assigned to adult patients suffering from:
- acute myeloid leukemia;
- myelodysplastic syndrome;
- chronic myelomonocytic leukemia.
As a rule, treatment with this agent is carried out under the condition that it is impossible to transplant hematopoietic stem cells in patients.
Why the price of a generic drug "Vidaza" is lower than the brand means
It's no secret that a lot of anticancerdrugs have a high cost. This sometimes leads the patients to whom they were assigned, in a difficult situation, because you have to buy more than one package.
In such cases, generic drugs come to the rescue.These are drugs with absolutely similar composition and also produced using the technology of the main brand means. The company producing them buys a license, but does not spend money on their development, studying the effects of the drug and the advertising company, so the price of a generic drug is much lower than that of a branded drug.
Thus, the Indian company Natco Pharma launches XPREZA, a generic of Vidaza, on the local market, which can be bought on the website . Here, patients at affordable prices are offered a large number of hospital-type medicines that can prolong and improve the quality of life of seriously ill patients.
Features of use and dosage of the drug
The drug "Vidaza" injected subcutaneously in the shoulder, thighor belly. Moreover, the injection area must be alternated, and the place of each subsequent injection should be at a distance of more than 2.5 cm from the previous one.
Please note that the drug should not be administered in places of seals, redness, hemorrhage or other damage.
Before the injection of Vidaza, it is recommended to take antiemetic drugs.
Для всех пациентов во время первого курса therapy, regardless of blood counts, the initial dose is 75 mg / m² of the entire body surface and is administered within a week, every day. Then there is a break for 21 days, after which the cycle repeats.
As a rule, the patient needs 6 cycles. But the treatment is continued until the efficacy of the therapy is visible, or until signs of progression of the pathology appear.
Preparation of solution for injection
For the procedure you need to dissolvethe contents of the bottle in water for injection (4ml). Having received a concentration of 25 mg / 1 ml, the suspension should be shaken vigorously until it becomes homogeneous and becomes white. If you need to get a dose higher than 100 mg, you should take 2 bottles of Vidaza.
Contraindications
In some cases, the appointment of the drug "Vidaza" the instruction to which is provided in this article is not allowed. As a rule, this occurs in these patients:
- with widespread liver metastases;
- in childhood;
- for those with increased sensitivity to the main active ingredient of the drug or other components thereof;
- during pregnancy and lactation.
Carefully use the said tool in patients with diseases of the heart, lungs, kidneys and liver.
Side effects
The most frequent side effects during therapy with the drug "Vidaza", the instruction calls the following:
- nausea and vomiting;
- constipation or diarrhea;
- abdominal pain;
- anorexia;
- dizziness and headache;
- drowsiness, weakness;
- fever;
- anxiety, sleep disorders;
- dyspnea;
- itching;
- petechiae;
- arthralgia;
- nasopharyngitis;
- pneumonia;
- anorexia.
