How should I use the drug "Reosorbilact"?The instruction and indications for the use of the said agent will be presented below. Also we will tell you about the form in which this medication is produced, its cost, whether it has analogs, side effects and contraindications.
Form of release, description, packaging and composition of the medicine
In what form are produced such a remedy as "Reosorbilakt"? The instruction attached to this drug says that it is marketed as a colorless, transparent solution for infusions.
The active substances of this medicine are:sodium lactate, magnesium chloride, sorbitol, calcium chloride, sodium chloride and potassium chloride. Also in the composition of this medication is an auxiliary component such as distilled water.
The drug is sold in glass bottles, which are placed in cardboard packages.
Pharmacodynamics
What is the drug "Reosorbilakt"?The instruction informs that this plasma-substituting agent. It has antishock, rheological, alkalinizing and detoxifying effects. The main pharmacologically acting elements of this drug are sodium lactate and sorbitol.
Entering the liver, the last component firstis converted into fructose, and then sequentially into glucose and glycogen. It should also be noted that one part of sorbitol will be consumed by the body for energy needs, and the other is postponed as glycogen.
The isotonic solution of this substance has a disaggregant effect. It improves perfusion and microcirculation of tissues.
Unlike the bicarbonate solution, the adjustmentacidosis (metabolic) with sodium lactate is much slower, as it is included in the metabolism. At the same time, there are no sharp fluctuations in pH. The effect of this substance occurs approximately 25-30 minutes after administration.
What other properties does the medicine have?"Reosorbilact"? The instruction says that calcium chloride, which is part of the drug, is able to eliminate the deficiency of calcium ions, which are extremely necessary for the reduction of smooth and skeletal muscles, blood clotting, transmission of nerve impulses, myocardial work and bone formation.
It should also be noted that thethe substance lowers the permeability of vascular walls and cells, prevents the development of inflammatory processes, significantly enhances phagocytosis, and also increases the resistance of the human body to various infections.
Sodium chloride is a kind of plasma-substitutingmeans. It exhibits rehydration and detoxification properties. The drug eliminates the deficiency of chloride and sodium ions, which occurs with various pathological conditions.
Калия хлорид способен восстанавливать electrolyte and water balance. It exhibits negative batmo- and chronotropic effects, and in high dosages - negative dromo- and inotropic diuretic effect (moderate expression).
The considered component takesdirect participation in the processes of conduction of nerve impulses. It increases the content of acetylcholine, and also promotes the excitation of the sympathetic part of the vegetative system. Also, the component under consideration improves the processes of skeletal muscle contraction in myasthenia gravis and muscular dystrophy.
Pharmacokinetic properties
Is the drug reosorbylact absorbed?The instruction (the price of the solution is presented a little further on) says that sorbitol is quickly incorporated into the general metabolism of the body. Approximately 80-90% of the active substance is utilized in the liver. In the same organ, sorbitol accumulates in the form of glycogen.
It should also be noted that 5% of the medicine is deposited in the heart muscle, brain tissue and skeletal muscle. About 7-12% of the drug is excreted together with urine.
After the administration of the drug inthe sodium channel of lactate begins to react immediately with water and carbon dioxide, forming sodium bicarbonate. This process leads to an increase in the alkaline reserve of blood.
Only ½ of the added sodium lactate is active. As for the other half, it is not metabolized and excreted in the urine.
Indications
In what cases is the drug "Rheosorbylact" prescribed? Instructions for use (the price of this tool is not very high) includes the following indications:
- sepsis;
- traumatic, operating, hemolytic, toxic and burn shock, acute blood loss, burn disease;
- to improve the blood flow of capillaries (with a preventive purpose);
- infectious diseases, which are accompanied by exacerbation of chronic hepatitis and intoxication;
- Raynaud's disease;
- for improvement of venous and arterial blood circulation with a preventive purpose;
- treatment of thrombophlebitis, thrombosis and endarteritis;
- in the postoperative period;
- for preoperative preparation.
Contraindications
At what deviations is it impossible to use the medicine "Reosorbilakt" (200, 400 ml)? According to the instruction, the following conditions are contraindications for the agent in question:
- alkalosis;
- if the patient is contraindicated injecting a large amount of fluid (for example, with thromboembolism, hemorrhage in the brain, cardiovascular decompensation, arterial hypertension of 3rd degree);
- hypersensitivity to drug substances.
It should also be noted that the medication in question is prescribed with extreme caution in patients with impaired liver function, hemorrhagic colitis, and peptic ulcer disease.
Dosage medication and methods of its use
In case of burn, traumatic, hemolytic and postoperative shocks, the dropper “Reosorbilact” is administered once in a volume of 600-1000 ml.
In chronic hepatitis, the dose of the drug is 400 ml.
In case of acute blood loss, the drug is prescribed in 1500-1800 ml.
After surgery, as well as in the preoperative period, the drug is administered drip in a volume of 400 ml. The procedure is carried out daily for 4-5 days.
In case of thrombocyte irregularitiesvas medication is prescribed at the rate of 8-10 ml per kg of patient weight. The drug is administered drip every other day. The duration of therapy is up to 10 infusions.
For children under six years old, this remedy is recommended to be used at a dosage of 10 ml per kg of body weight. For children from 6 to 12 years old, the drug is prescribed in half the dose for adults.
Side effects
Does the side effects causedrug "Reosorbilakt"? Analogs and the considered tool itself almost never become the causes of undesirable effects. However, in some cases, patients may still have alkalosis and allergic reactions in the form of itching and skin rashes.
Features of the medicinal product
The drug in question should be usedonly prescribed by a doctor. Moreover, the solution must be administered only under the control of indicators of blood electrolytes and the acid-base state of the body, as well as the work of the liver.
With extreme caution, this medication is prescribed to patients with calculous cholecystitis.
Terms, methods and conditions of storage
Considered medication belongs to the list B.This drug should be stored only protected from light, dry and out of reach of children. The storage temperature of the drug is from 5 ° to 26 ° C. Its shelf life is two years. After this period, the use of the drug is prohibited.
Drug "Reosorbilakt": price and analogues
Synonyms and analogues of the drug "Reosorbilact"sold in all pharmacies. Among the most common and effective means are the following drugs: Sorbilact, Potassium Chloride, Potassium Chloride Bufus, Calcium Chloride, Consol, Cormagnesin, Custodiol, Magnesium Sulfate
How much does Reosorbilact medicinal solution cost? The price of this tool in pharmacies may vary for different reasons. However, on average, such a drug costs about 200 rubles (200 ml).
Drug reviews
According to patient reviews, the drug solution"Reosorbilakt" effectively treats acute blood loss, sepsis, burn diseases, infectious diseases, and also eliminates the shock. Another advantage of this drug is that it almost never causes side effects. Although in some cases it still causes the appearance of allergic reactions.
