Drug form of the drug "Concor": The instruction states that the drug is supplied intablets that are film-coated. The biconvex tablets are pale yellow and have a heart shape. On each of the surfaces there are dividing risks. Tablets are of two kinds, differing in concentration.
Composition:
Active substance:
- Bisoprolol gemifumarate - 5/10 mg (in 1 table, respectively)
Excipients:
- Anhydrous calcium hydrogen phosphate
- Anhydrous Colloidal Silicon Dioxide
- Magnesium stearate
- Microcrystalline cellulose
- Crospovidone
- Corn starch
pharmachologic effect
The drug belongs to the group of beta 1 adrenoblockers, which do not have their sympathomimetic activity. The drug also does not have a membrane-stabilizing action.
Concor reduces the activity of renin, reducesthe need for oxygen in the myocardium, reduces the heart rate. It also has antiarrhythmic, anti-anginal and hypotensive effects. When the dose is increased, the drug can act as a beta 2 adrenoblocker.
On the first day of taking the drug OPSS increases, and after a few days returns to normal. With prolonged use of the drug OPSS may be reduced.
Antiarrhythmic effect of the drug is associated with itsthe ability to reduce the need for oxygen in the myocardium, reduce the action of the renin-angiotensin system, and stimulate sympathetically peripheral vessels.
Concor indications for use
- CHD
- Arterial hypertension
- Chronic heart failure
Side effects of concor
The manual describes almost all the symptoms that can be caused, as a consequence of the side effects of the medication.
Side effects associated with the gastrointestinal tract:
- Vomiting
- Nausea
- Constipation
- Diarrhea
- Dryness of the oral mucosa
- Hepatitis
Side effects associated with SSS:
- Bradycardia
- Arterial hypertension
- Angiospasm
- Arterial hypotension
- Angiospasm
- Violation of AV conduction
- Arterial hypertension
- Decompensation of heart failure
Side effects associated with the central nervous system:
- Asthenia
- Dizziness
- Headache
- Depression
- Sleep disturbance
- Increased fatigue
- Nightmares
- Convulsions
- Hallucinations
Side effects associated with the organs of vision:
- Reduction of lacrimation
- Conjunctivitis
- Visual impairment
Side effects associated with reproductive system:
- Violation of potency
Possible allergic reactions to the drug:
- Rash
- Itchy skin
- Skin redness
Side effects that can be associated with dermatological causes:
- Alopecia
- Sweating
- Psoriasis
During the course of taking the drug, you can not dramatically change the dose of the medication and terminate the medication, because it can give a complication to the heart, especially for patients with ischemic heart disease.
Contraindications to the drug "Concor"
The instruction includes a list of diseases in which taking the drug is not recommended.
- AV blockade of 2 and 3 degrees
- Collapse
- Cardiogenic shock
- Pronounced bradycardia
- Heart failure
- Sino-arterial block
- Acceptance of MAO inhibitors (except type B)
- Pronounced lowering of blood pressure
- COPD and severe bronchial asthma
- Raynaud's disease
- Metabolic acidosis
- Pheochromocytoma
- Age under 18 years old
- Sensitivity to components
In addition, this drug must be used.very carefully if the patient has a history of liver failure, thyrotoxicosis, diabetes, myasthenia, renal failure, Prinzmetal angina, psoriasis, depression.
Overdose drug "Concor"
The instruction states that in the event of an overdose, it is necessary to flush the stomach, take absorbents and prescribe symptomatic therapy to the victim.
Drug interactions drug "Concor" box
The instruction does not contain descriptions of the consequences.Concor interactions with other drugs. Concor quite often can mutually affect the effectiveness of drugs used simultaneously with it.
