Lidaza electrophoresis: methods and scope of application

Drug electrophoresis is a physiotherapeutic technique, which is based on the combined effect of electric current and certain pharmacological preparations.

When applying this technique is positiveThe biological effect of direct current is enhanced by the pharmacological effect of drugs, which is associated with their electrophoretic activity in the electromagnetic field.

Today, quite often usedelectrophoresis with lidazy. In this case, the solution of this substance dissociates into ions, which are converted into charged hydrophilic complexes. If this solution is placed in an electric field, then the ions begin to move to the opposite poles. If biological tissues are on their way, then electrically charged particles of medicine will penetrate into them and show the corresponding therapeutic effect. In this case, the drug first penetrates the epidermis and dermis, and then into the interstitium and endothelium of the blood and lymphatic vessels.

Lidaza electrophoresis is often prescribed for earlyformation of hypertrophic type scars. During this period, fibroblasts actively synthesize hyaluronic acid, therefore, to reduce skin defects, you should use a specific enzyme, hyaluronidase (lidazu).

It is worth noting that electrophoresis with lidaza cancombined with collagenase, gamma-interferon, as well as with prednisone or dexamethasone, since corticosteroids inhibit the proliferation and synthesis of fibroblasts, block the enzymes that are responsible for the synthesis of collagen, reduce the vascular permeability.

It should also be said that electrophoresis with lidazamay be prescribed for lesions of the joints, when their stiffness, deformation, and pain syndrome occur. It is precisely to alleviate these symptoms that electrophoretic administration of lidaza is used, which is alternated with novocaine solution, which makes it possible to alleviate the condition of patients after 5-6 sessions.

Electrophoresis with lidazy is used ingynecological practice. So, this physiotherapeutic procedure is performed for women with adhesions in the reproductive organs, as well as for infertility.

It must be remembered that any drug canan allergic reaction develops, therefore, before applying electrophoresis with lidaza, an intracutaneous test for this drug must be carried out.

How is the electrophoretic injection of drugs?

При проведении электрофореза накладываются electrodes with gaskets, which are made of filter paper and pre-wetted in a solution of the drug. In this case, two electrodes are placed on the lower third of the leg, two more - on its upper third. The procedure should last 20 minutes and be carried out at least 10 times. After three months, the treatment is repeated if necessary.

For those patients who can not constantly attend a physiotherapy room, electrophoresis is performed at home.

It is also worth mentioning the method thatis becoming common in molecular biology - DNA electrophoresis. It is used for cloning, sequencing and determining the amount of deoxyribonucleic acid.