Our body is a complex system that canvery well protected from external influences. But in the world there are many pathogenic microorganisms and fungi that are looking for an opportunity to break the protective barriers of the body and use it for their own needs. Symptoms of infection with these simple organisms are mycoses. The disease is not too dangerous, but it greatly reduces the quality of life, as it causes severe discomfort and many cosmetic problems.
What are mycoses?These are diseases of the skin and nails, hair and internal organs of a person, the causative agent of which are fungi belonging to conditionally pathogenic microflora. On guard of health is such a drug as "Irunin." Analogs, cost and range of actions we will consider today.
What is the drug "Irunin"
Это в первую очередь противогрибковое средство broad spectrum. The main active ingredient - itraconazole - violates the integrity of pathogenic fungi and prevents their reproduction. At the same time there are microorganisms that are more or less sensitive to this substance. It is most effective in relation to dermatomycetes, moldy fungi, Candida-type yeast fungi. However, there is not only Irunin on the market. Analogs provide a wide choice and an opportunity to regulate expenses for treatment. Below we take a closer look at the price range of these medicines.
Pharmacological properties
Let's look at the mechanism of action of the drug."Irunin". Instructions for use (the price of this drug does not at all indicate poor quality) presents it to us as an antimycotic drug of broad spectrum. The active ingredient disrupts the life cycle of fungi by preventing the production of ergosterol by the membrane of their cells. The drug effectively destroys dozens of different varieties of fungi. The maximum concentration in the blood is reached after approximately 4 hours. Decay products are completely eliminated from the body approximately 7 days after the cessation of treatment. At the same time, the therapeutic concentration in the epidermis persists for about a month. In keratin nails, the drug will retain its healing power for about 200 days after the end of the 90-day course of treatment.
Indications
Where is primarily used "Irunin"(analogs)? This is dermatology (it is most often prescribed for ringworm and multi-colored lichen), as well as gynecology. The very first problem with which women go to a consultation is candidiasis (or thrush). Especially effective drug for candidiasis with lesions of the mucous membranes and skin, onychomycosis, vulvovaginal thrush. In this case, it is most often appointed “Irunin”. Analogs are not much inferior to him in terms of efficiency, but are less widely distributed means.
Contraindications
However, not all cases can be assigneddrug "Irunin". Its use in childhood is strictly prohibited, it is also prohibited in the first trimester of pregnancy. Starting from the 4th month of pregnancy, this drug can be administered only if the intended benefit to the mother is higher than the possible risk to the fetus. The physician should be very careful when prescribing a drug to people suffering from heart failure, chronic lung and respiratory diseases, or serious liver damage.
Side effects
They are serious enough, so you shouldcarefully review their list before making a decision about taking the drug. Antifungal tablets due to the broad spectrum of action can not only provoke various side effects, but also affect virtually all vital systems. In addition, each of them can respond to different manifestations. Thus, the digestive system often responds to the effects of the drug with various disorders and extremely rarely with intoxication and damage to the liver. The central nervous system often responds with migraine attacks, drowsiness and dizziness. Women may experience a failure of the menstrual cycle. There are allergic reactions in the form of skin rashes, pulmonary edema is possible.
It should be noted that most often antifungalpills are well tolerated, but any of the side effects may occur with varying degrees of probability. Therefore, do not self-medicate, but contact the doctor who will select the most appropriate means for you.
Forms of release and method of application
The most popular antifungal agentare tablets "Irunin". Instructions for use tells us that the drug is a yellow round pills that should be used, according to the specified scheme. With candidal vulvovaginitis - 0.2 g twice a day, with multi-colored lichen, the dosage can be halved. The same dose (0.2 g once a day) is maintained in the treatment of fungal keratitis, ringworm. In some cases, it is recommended to reduce the dosage to 0.1 g per day. This is in diseases such as oral candidiasis and fungal skin lesions.
The second dosage form is the Irunin candle.They are prescribed for thrush. The method of application is classic: every day before bedtime you need to insert one candle deep into the vagina. The duration of treatment is usually not more than two weeks. If you are desperate to find a solution to a delicate problem, ask your doctor about the possibility of using the drug Irunin. Vaginal suppositories are very effective in controlling diseases such as candidiasis.
Overdose
To date, information about overdose is notnever did. Nevertheless, it must be remembered that it is impossible to violate the regimen prescribed by a doctor, as well as increase the dosage. If there is a suspicion of using a large dose of the drug, you should wash the stomach and give the person activated charcoal. There is no antidote, as the use of a high dose of the drug is not life-threatening. Despite this, it is necessary to conduct a general strengthening therapy.
How much is "Irunin"
Against the background of the advertised "Diflukan" and himsuch drugs, the price of "Irunin" is quite reasonable. The cost of packing capsules 0.1 mg - 330 rubles. One pack contains 14 capsules. At the same time, candidiasis is treated by double ingestion of capsules of 0.2 g (in the morning and in the evening) or for three days, one capsule of 0.2 mg per day. As you can see, the drug Irunin is very affordable and economical. The price of the tablet does not exceed 30 rubles.
In the treatment of scaly depriving the scheme a bitchanges, appoint 200 mg once a day, the treatment lasts up to 7 days. The most difficult to treat diseases, such as aspergillosis, cryptococcosis, histoplasmosis, sporotrichosis, require a long course from two months to a year. At the same time every day the patient should not take more than 200 mg of the drug. But even in this case, treatment with the drug Irunin is quite affordable. The price of the pill is almost 10 times lower than the capsules of "Flucanosol", which is also often prescribed for thrush and other problems.
Drug "Orungal"
This is the original drug onthe basis of which then began to produce a variety of generics, that is, drugs that are based on clinical studies of its original progenitor. The absence of the need to invest time and money in long-term development allows manufacturers to maintain a more attractive price. We have already spoken about how much Irunin costs. Now, for comparison, let's look at the average prices for Orungal. For the same 14 capsules you will give at least 2500 rubles, that is, at least five times more expensive.
It should be noted that in the market there are threeoriginal antifungal drug. This is Orungal, which specializes in the treatment of skin fungi covered with hair (this may be the head, chest or back); "Lamisil" - specializes in the treatment of nail fungus and is absolutely useless for the treatment of mucous membranes and internal organs - this is the field of activity of "Diflucan". In turn, "Orungal" is also used to treat fungal lesions of the oral cavity, vagina, intestines and bronchi.
Other analogues
На фоне всех представленных на рынке Antifungal drugs most popular is "Irunin." Instructions for use, reviews of doctors and patients - all confirms the high efficacy and reliability of the drug. It is very difficult to find another so successful combination of price and quality on the market. In addition to the above analogues, doctors can offer you the drug "Itrazol", it is very close in cost and will cost about 400 rubles per pack.
Another popular counterpart is"Orungamin". The cost is about the same as the spectrum of action. The most reliable is the anti-fungal drug "Orungal", it is not the cheapest treatment option, but clinical studies confirm its highest efficacy.
Drug Interactions
How safe is it to start treatment with others?drugs, if you are taking "Irunin"? The instruction (the price of this brand is the most attractive, so we pay more attention to it) says that in some cases it will be necessary to interrupt the course if there is an urgent need to take other drugs. This applies to drugs such as rifampicin, rifabutin, difenin. And the point is not that the interaction of these drugs with Irunin has a harmful effect on the body. These drugs activate the activity of liver enzymes, which in turn reduces the effectiveness of itraconazole.
There are drugs that are the oppositeenhance the effectiveness of the active ingredient "Irunina". These are medicines such as erythromycin and ritonavir. In combination with antifungal drugs, drugs such as terfenadine and astemizole, halcion and flormidal, quinidine, oral, zocor, lovastine, mizolastine, cyzaparide should not be taken.
Pregnancy and lactation period
Во время беременности угроза поражения грибком Candida doubles. But it is during this period that treatment with the help of the drug "Irunin" is strictly prohibited. They can not only negatively affect the fetus, but also cause severe malformations. Therefore, the expectant mother is offered maintenance therapy with the help of folk remedies. During the lactation period, the child's body also receives all the medicines that the mother takes. Therefore, without good reason, you should not take any medication. This should be remembered for all women of reproductive age. If you are prescribed a long-term treatment with such a serious drug, then you need to be protected by reliable means to avoid an accidental pregnancy. After the end of the course of treatment, at least three months must pass before planning for pregnancy.
