/ / The drug "Nimesulide". Instructions. Indications, contraindications, side effects.

The drug "Nimesulide". Instructions. Indications, contraindications, side effects.

The drug "Nimesulide" ("Nise") refers to the groupNSAIDs (anti-inflammatory nonsteroidal drugs). The drug is made in the form of conventional tablets, dispersible tablets (fast acting) and for resorption, granules for the preparation of syrup and solution, suspension. The active ingredient is nimesulide.

The drug has anti-inflammatory, analgesic, antiagritant and antipyretic activity. The remedy reduces pain and inflammation. The medicine does not affect the progression of pathology.

The drug "Nimesulide" instructions are recommended whenarthritis of different nature, osteoarthritis, rheumatoid arthritis, bursitis, tendonitis. The drug is prescribed for acute pain syndrome, for the elimination of post-traumatic and postoperative pain, for algomenorrhea, headache, toothache, myalgia, arthralgia. The tool "Nimesulide" instruction recommends using for symptomatic treatment.

The drug is not prescribed for bronchial asthma,recurrent polyposis in the paranasal sinuses or nose, hypersensitivity, individual intolerance to acetylsalicylic acid and other NSAIDs (including in the history of the disease). The drug "Nimesulide" instruction does not allow for use in erosive and ulcerative lesions in the digestive system, active gastrointestinal, cerebrovascular and other bleeding. Contraindications include inflammation in the intestines, hemophilia and other disorders of blood coagulation function. The drug is not prescribed for decompensated heart failure, liver failure, or any pronounced pathology of the liver. The medicine "Nimesulide" instructions do not allow to use with progressive renal diseases, with a history of hepatotoxic reactions when using the medication, confirmed by hyperkalemia. Not recommended remedy after coronary artery bypass surgery, while the use of hepatotoxic drugs. Contraindications include pregnancy, lactation. The drug "Nimesulide" is not prescribed for children under twelve years of age.

The drug is taken after meals. The recommended dose is twice a day, fifty or one hundred milligrams.

When using the drug may occurvarious side effects. The drug can cause allergies, anaphylactic reactions, dizziness, Reye's syndrome, drowsiness, headache, nervousness, fear, nightmares. When taking the drug may be an increase in sweating, angioedema, dermatitis, urticaria, erythema, swelling of the face. Side effects include epidermal necrolysis (toxic), Stevens-Johnson syndrome, pruritus and skin rash. Among the undesirable effects observed urine retention, dysuria, kidney failure, hematuria, interstitial nephritis, oliguria. Often, when taking the medication occurs nausea, diarrhea, emetic urge. The drug can provoke constipation, gastritis, flatulence, tarry stools, stomatitis, epigastric pain. Bleeding in the digestive tract, gastric or duodenal ulcers, cholestasis, jaundice, and hepatitis (including fulminant) may also develop. The medicine Nimesulide in some cases causes hemorrhage, purpura, thrombocytopenia, eosinophilia, dyspnea, anemia, asthma exacerbations, bronchospasms. In rare cases, there may be a violation of clarity of vision, tachycardia, a decrease in blood pressure, flushing to the face and upper body, hypothermia, and general weakness.

Experts do not recommend the use of the drug "Nimesulide" for patients planning a pregnancy due to the ability of the drug to adversely affect fertility.

The drug can reduce the speed of psychomotor reactions. Therefore, care must be taken when carrying out potentially hazardous activities.

Before taking the medicine "Nimesulide" should be carefully studied instructions.