"Secnidazole" is an antimicrobial, antiparasitic and antibacterial agent. In this article we will talk about this drug, its use and analogues.
Pharmacological properties
This medication is asynthetic derivative of nitroimidazole. The drug is active against protozoal infections, as well as most anaerobic bacteria. The medicinal product does not influence aerobic bacteria. This confirms the instructions for use with "Secnidazole". Analogues will be presented below.
Indications
This drug is prescribed for vaginitis and urethritis, caused by Trichomonas, liver and intestinal amebiasis, giardiasis.
Dosing and Administration
With vaginitis, giardiasis and intestinal amoebiasis inadults take the drug once in a dosage of 2 g, in children - 30 mg / kg. For liver amebiasis, adults take 1.5 g per day, children - 30 mg / kg for five days. In the treatment of liver amebiasis, drug therapy should be combined with the elimination of an abscess. With long-term therapy, it is necessary to monitor blood formulas. In patients with leukopenia, continued treatment is determined by whether there is a risk of developing an infection. Unfortunately, the instruction analogs does not indicate the means "Secnidazole".
Contraindications and side effects
The main contraindication is allergicreaction and age to 18 years. Also, the drug is not used in the active stage of organic pathology of the central nervous system, with pathological changes in the blood formula, during lactation and during pregnancy.
The description and analogs of "Secnidazole" interest many.
This drug is not prescribed to patients withhistory of blood disorders. Caution should be used "Secnidazole" drivers and other members of the professions associated with increased concentration. Side effects are expressed in the form of violations in the digestive system, metallic taste in the mouth, stomatitis, glossitis, urticaria, leukopenia, dizziness, ataxia, impaired coordination of movements, polyneuropathy. If dizziness, ataxia and other signs of deterioration of the neurological status appear, treatment should be canceled immediately.
Overdose
In case of overdose, symptomatic and supportive treatment should be carried out. Analogs of "Secnidazole" can also be clarified with a doctor.
Drug Interactions
Taking the drug with alcohol categoricallyimpossible, as possible complications such as nausea, vomiting, abdominal cramps, headaches. At the same time, there is confusion, psychotic states and paranoid reactions. Secnidazole enhances the anticoagulant effect of drugs such as warfarin, indandione, coumarin derivatives. In addition, it increases the risk of bleeding, as the hepatic metabolism of anticoagulants decreases. As necessary, the dosage of coagulants should be adjusted throughout the entire course of therapy and within a week after it. Sharing with amoxicillin enhances effectiveness against Helicobacter pylori. The drug increases the concentration of lithium in the blood in the case of simultaneous use with drugs containing lithium. In addition, the treatment increases the hypoglycemic effect of insulin and glucose-lowering agents.
Analogs of "Secnidazole"
By synonymous analogues containing a related active ingredient, include drugs such as "Safotsid", "Tager". We will tell you more about each of them.
"Tager"
"Tager" belongs to the same group of drugsas described drug, the active substance is the same - secnidazole. Available in the form of granules. Pharmacological action is characterized by antimicrobial and bactericidal action against anaerobic bacteria. Indications for use are the same as in the original: urethritis, vaginitis, intestinal amebiasis and liver, giardiasis. Side effects and contraindications also coincide.
The treatment regimen and the recommended dose determinesThe doctor, but the general recommendations about application look as follows: at a urethritis, a vaginitis, a giardiasis reception of 2 g once is shown. In intestinal amebiasis, adults take 2 g, children 30 mg / kg once. With asymptomatic amebiasis for adults - 2 g, for children - 30 mg / kg once a day for 72 hours. In case of purulent amebiasis, it is necessary to combine drug therapy with the removal of pus. Instructions on the categorical ban on the use of alcohol with the medication also have a place to be. What other analogs to Secnidazole are available?
"Safotsid"
"Safotsid" - a combination drug that providesantifungal and antibacterial action against the simplest microorganisms. The composition of the drug includes three types of tablets of different colors:
- The first group is pink fracture tablets, which contain fluconazole.
- The second group consists of tablets with white contents inside which contain azithromycin.
- And the third group consists of white and inside and outside tablets with secnidazole.
Analogs of "Secnidazole" in Russia can be purchased at any pharmacy chain.
In one package is:1 tablet of fluconazole, 1 tablet of azithromycin and 2 tablets of secnidazole. Fluconazole is responsible for the anti-mycotic effect by inhibiting the activity of the fungal infection. Azithromycin inhibits the spread and growth of pathogenic bacteria. Secnidazole is an antimicrobial agent that suppresses anaerobic bacteria. This drug is recommended for infectious diseases of the urinary tract and sexually transmitted infections. "Safotsid" is contraindicated for use in organic lesions of the central nervous system, renal failure, blood diseases, pregnancy and breastfeeding. As side effects, nausea, diarrhea, pain in the epigastric region, tachycardia, and allergic reactions are possible. The drug is taken one hour before meals. It is necessary to drink the entire set of tablets at one time and drink plenty of water.
So, we looked at analogues of Secnidazole.
