How to use the cream "Candidates"?Instructions for the use of external means are presented in the materials of this article. It also describes the reviews of the above drug, lists its indications and contraindications.
Description, composition and packaging of the drug
What packaging is available in the Candidem cream? Instructions for the use of this tool is enclosed in a box of cardboard. It also contains an aluminum tube with a drug substance.
The active ingredients of this medication areclotrimazole, beclomethasone dipropionate and gentamicin sulfate. It also includes auxiliary ingredients in the form of cetomacrogol, sodium dihydrogen phosphate monohydrate, sodium hydrogen phosphate, methyl paraben, benzyl alcohol, propylene glycol, vaseline, propyl paraben, liquid paraffin and water.
Ointment "Candidates" has a uniform texture and white color. This drug does not have any characteristic odor.
Pharmacological indicators of local drugs
What is a cream "Candidates"? Reviews of specialists say that it is antifungal, antimicrobial, antiallergic and anti-inflammatory agent with a combined composition.
Such an active substance of the drug, asbeclomethasone has antipruritic, anti-allergic, anti-exudative and anti-inflammatory properties. Its mechanism of action is based on reducing the leukocyte accumulation process, releasing inflammatory mediators and specific lysosomal enzymes, inhibiting the process of phagocytosis, and also preventing the formation of puffiness and reducing vascular tissue permeability.
An ingredient such as gentamicin isis an antibiotic. It belongs to the aminoglycoside group, and also has a bactericidal effect. It can not be said that this component is able to suppress the activity of Klebsiella, Proteus, Pseudomonas, Enterobacteria, Streptococcus, Escherichia and Staphylococcus.
As for such a substance as clotrimazole, it has anti-fungal properties. Its mechanism of action is based on a decrease in the synthesis of ergosterol, that is, an integral part of fungal cells.
Pharmacokinetics means
What kinetic parameters does the cream have?"Candidate"? The instructions for use do not contain any information on this subject. Manufacturers explain this fact that the ointment in question has a combined composition. This makes it difficult to track its pharmacokinetic features.
Cream "Candidates": testimony
The considered drug is well manifested in the following diseases:
- athlete's foot;
- phleboderma;
- dermatosis with secondary infection;
- allergic dermatosis;
- ringworms (including those with inguinal lesions);
- dermatitis after insect bites;
- diffuse form of neurodermatitis;
- eczema;
- red lichen;
- atopic dermatitis;
- anogenital itching.
Contraindications
External drug "Candidates", whose analogues are listed below, is prohibited to use in the following pathological conditions:
- chicken pox;
- trophic wounds;
- individual hypersensitivity;
- rosacea;
- open wound surfaces;
- post-vaccination reactions on the skin;
- acne vulgaris;
- viral skin lesions;
- tuberculosis of the skin;
- syphilitic reactions on the skin.
Cream "Candidates": instructions for use
Рассматриваемый препарат следует наносить на affected skin twice a day (after waking up and before bedtime). The duration of such therapy depends on the individual tolerance of the patient and the overall effectiveness of the treatment process.
After 4 weeks of active use of the cream, the patient may show the first undesirable effects.
Do they use the Candidem ointment in pediatric practice? Reviews of doctors report that the age limit on the use of this tool is a period of life up to 16 years.
If necessary, by decision of the attending physician, this medication can be prescribed to children aged 7-16 years.
Side effects
What are the side effects of the drug "Candiderm" (cream)? The instruction states that long-term therapy with this remedy can lead to such systemic reactions as depression of the adrenal cortex.
With proper use of the drug, negative effects are extremely rare, and are also mild and temporary.
So, against the background of the use of the “Candidates” product, patients may experience the following allergic responses:
- striae, contact dermatitis, maceration, urticaria;
- dry skin, swelling, peeling, hyperemia;
- telangiectasia, furunculosis, hypertrichosis, pyoderma;
- burning sensation, perioral dermatitis, hypopigmentation, folliculitis;
- acne steroids, prickly heat, atrophic changes on the skin.
Drug overdose
When applying a large amount of cream on large areas of the skin of a patient, the following symptoms of overdose may occur:
- weight gain;
- hypokalemia;
- increased blood pressure;
- glucosuria;
- manifestations of hypercortisolism.
With such deviations, the patient is subjected to electrolyte balance correction, as well as post-syndromic therapy is performed.
Special Recommendations
It is forbidden to use the Candidem ointment in ophthalmic practice. Also, this drug can not be applied to the skin, located around the eyes.
Occlusive dressings significantly increase the effectiveness of the medication.
When using this medicine with bandagestransdermal absorption of its active elements (in particular beclomethasone and gentamicin) may be enhanced. This can cause negative systemic reactions.
When observing fungal and bacterial resistance, the drug is canceled.
In the treatment with aminoglycosides, the development of cross-resistance is characteristic.
In pediatric practice, “Candidirm” ointment is used only according to indications and under medical supervision.
Drug application and dressing over large areas of skin can lead to suppression of the pituitary-hypothalamic-adrenal system.
Analogues of the drug and its cost
What can replace the cream "Candidates"?Analogues of this tool are sold in all pharmacies and are sold without a medical prescription. The most popular substitutes for the mentioned medicament are the following: Belogent, Betagenot, Betaderm.
How much does the Candiderm ointment cost? The price of this local remedy is quite high (according to most patients). You can buy one tube of antifungal drug for 450-470 rubles.
Reviews about the drug
Doctors confer a unique cream "Kaderm"antifungal, anti-pruritic and anti-inflammatory properties. They leave only positive reviews about this drug. According to their opinion, the medication in question is fairly well tolerated by patients and in a short time allows to achieve the desired result.
As for patients, they also speak about the high effectiveness of this medicine. After several cream application, the signs of most skin diseases are significantly reduced.
