The drug is available in tablets in a whitish color or in the form of a solution for injection.
The tablets are biconvex, round in shape.
Composition:
Active substance
- Etamsylate 250 mg (in 1 table)
Excipients:
- Anhydrous citric acid
- Povidone K25
- Corn starch
- Lactose
- Magnesium stearate
The solution is clear, colorless.
Composition:
Active substance:
- Etamsylate - 125/250 mg (in 1 ml and in 1 ampoule, respectively)
Excipient:
- Sodium disulphite
- Sodium bicarbonate
- Water for injections
pharmachologic effect
The drug has hemostaticaction. In the walls of capillaries, the drug can increase the synthesis of mucopolysaccharides, while normalizing their permeability and improving microcirculation. The drug can normalize the adhesion of platelets and stimulate the synthesis of clotting factor. But the drug can not have any effect on prothrombin time, and it also lacks hypercoagulable properties and the ability in principle to thrombogenesis.
Pharmacokinetics
After the administration of the drug, its maximumconcentration in the blood is detected after 10 minutes. In the event that the drug was taken in the form of a tablet inside, it is absorbed into the gastrointestinal mucosa very quickly and almost completely. The drug can penetrate the placental barrier, and it can also be easily excreted along with breast milk. This is why it is necessary to use this medicine with caution if the patient is pregnant or nursing a newborn baby.
Indications for use of dicinone
The instruction says that the drug is intended for the treatment and prevention of various capillary bleedings:
- Metrorrhagia
- Hematuria
- Menorrhagia
- Bleeding gums
- Nose bleed
- After and during surgery in various areas of medicine
- Intracranial hemorrhage in premature infants and newborns
- Diabetic microangiopathy
Before you start taking the drug, you need to most accurately exclude the possibility of other causes of bleeding.
The drug in the form of a solution is intended for use exclusively in a hospital. In order to learn how to take dicinone, you need to contact your doctor.
Side effects of the medicine "Dicinon"
The manual describes all the side effects,which manifested itself or could manifest itself in the control group during the testing of dicinone. The preparation, in addition, may have other side effects not included in the list below, due to the individual allergic reaction of the patient to one or more components of dicinone.
Side effects that can be associated with the peripheral and central nervous system:
- Dizziness
- Headache
- Paresthesia of the lower extremities
Side effects that can be associated with dermatological reactions of the body:
- Hyperemia of the face of the skin
Side effects that can be associated with the gastrointestinal tract:
- Gravity in epigastrium
- Heartburn
- Nausea
Side effects that can be associated with CAS:
- Decrease in systolic pressure
Contraindications to the use of the medicine "Dicinon"
The manual describes the diseases in which the drug is not recommended:
- Children's hemoblastosis
- Acute porphyria
- Thromboembolism
- Thrombosis
- Sensitivity to components
Drug interaction of the drug "Dicinon"
The instruction of this section is presented in a truncated form and may include other results of the interaction of the described preparation with other drugs.
You can not combine this drug with others in one syringe.
The combination with aminocaproic acid and bisulfite of menadione sodium is possible.
Do not use together with a solution of sodium bicarbonate and sodium lactate.
