Drug "Kordinorm", instructions for use reports, is made in the form of tablets, film-coated. The international non-proprietary name is bisoprolol.
One pill contains five milligramsbisoprolol fumarate - the main active ingredient. Additional ingredients are macrogol 6000, microcrystalline cellulose, mannitol, magnesium stearate and titanium dioxide.
В продажу поступают таблетки массой пять либо ten milligrams. On one side there is a risk and engraving "B5" or "B10". The drug belongs to the pharmacotherapeutic group of selective beta-1 adrenergic blockers.
Considered means "Kordinorm" instructionreports, provides a reduction in myocardial oxygen demand, as well as a reduction in the frequency of contractions of the heart, both at rest and during exercise.
The drug is characterized by a high degreeabsorbability (about eighty to ninety percent), and the consumption of food does not affect absorption. In addition, the drug penetrates the placental and blood-brain barrier in minimal amounts. In breast milk, a small amount is found.
The period during which the drug is halfexcreted from the body, can be from nine to twelve hours. About ninety-eight percent is excreted through the kidneys, the other two - with bile.
Pharmaceutical preparation "Kordinorm" instructions prescribes for use in hypertension, coronary artery disease, as well as for the prevention of strokes.
Specified drug is contraindicatedin case of hypersensitivity of the patient to bisoprolol and its other components. It is not prescribed for pulmonary edema, cardiogenic shock, collapse, acute or chronic heart failure, severe bradycardia, cardiomegaly, arterial hypotension, bronchial asthma, obstructive pulmonary disease in the chronic stage, simultaneous administration of MAO inhibitors, Raynaud's disease, pheochromocytoma, metabolic acidosis, a also to persons under the age of eighteen.
Drug "Kordinorm" instructionemphasizes, with extreme caution, appointed if the patient suffers from diabetes, myasthenia, thyrotoxicosis, liver or kidney failure, depression, psoriasis. Elderly patients taking this medication require constant monitoring by a specialist.
The drug "Kordinorm." Instructions for use
The specified drug shouldapply two and a half to five milligrams at a time. Tablets are taken orally, in the morning before meals, without chewing. The daily volume is usually 5 mg, if necessary, it can be doubled (as recommended by the attending physician). Elderly patients do not adjust the dose.
Possible side effects:weakness, dizziness, fatigue, headaches, sleep disturbances, nightmares, depression, tremor and some other disorders of the central nervous system. In addition, a decrease in the production of tear fluid, blurred vision, conjunctivitis, dryness of the eyes and mucous membranes of the oral cavity, pain in the abdomen, vomiting, nausea, and malfunctioning of the liver are not excluded. Hypersensitive patients had a skin rash, itching, urticaria and other allergic reactions.
An overdose of Kordinorm, patient reviews confirm this, accompanied by severe headaches, fainting, convulsions, bronchospasm, difficulty breathing.
It is noted that the simultaneous use of nonsteroidal anti-inflammatory drugs and this medication weakens the hypotensive effect produced by the latter.
The drug "Kordinorm" released only with a prescription.
