The drug "Lotseril" is antifungaldrug for local use. It is used for the treatment of nail lesions (onychomycosis) caused by dermatophytes, molds and yeasts, as well as for the prevention of nail fungus lesions.
Medicine "Lotseril", reviews of which are completelypositive, produced in the form of nail polish with a 5% content of amorolfine - the active active ingredient. The package includes swabs for cleaning, spatulas and disposable nail files.
Pharmacokinetics of the drug "Loceryl"
Reviews pharmacists describe the therapeutic effectmedication. The active substance from the lacquer enters the nail plate, and then into the nail bed, where it stops the reproduction of fungi, causing their destruction. The therapeutic concentration of the drug remains in the affected organ for a week; with prolonged use, the medicine does not accumulate in the body.
Amorolfine slows down the production of enzymesinvolved in the biosynthesis of fungal cells, reduces the content of ergosterol, destroys the structure of fungal cells. Depending on the concentration of the drug has fungistatic or fungicidal effects.
Indications for use of the drug "Loceryl"
Reviews of doctors recommend the use of medicinefor the treatment of nail diseases caused by fungi, in cases of more than two thirds of the damage to the nail plate. The drug is also prescribed for prophylactic purposes.
Dosage and administration of the drug "Loceryl"
Patient testimonials indicate that varnishmust be applied to the nails twice a week. Before the first use of the tool should be as possible to remove the affected areas of the nail, using for this file. Then the nail surface needs to be degreased and processed with tampons moistened with alcohol. At the next use of varnish, the affected nails are again removed with a file that cannot be reused. Medicine "Lotseril" is applied to the surface of the nail with a spatula. Before processing the next finger, the spatula must be dipped into the lacquer, it is forbidden to wipe the excess money on the neck of the bottle. After the procedure, the nails should dry for three to five minutes.
Medication is continued continuously untiluntil the new nail grows or the affected areas are completely cured. The duration of therapy depends on the location of the infection and its severity. Usually, the standard course of treatment of finger nails lasts six months; for nails of toes, it will take from nine months to a year.
Contraindications side effects of the drug "Loceryl"
Reviews of patients using the toolindicate a slight burning sensation around the circumference of the nails after applying the lacquer, which soon passes. This is caused by the action of the solvent. Contraindications are practically absent. Do not use the drug to children, as well as people with individual intolerance to the components of the drug.
Due to the lack of information on the effect of the drug on pregnant and lactating mothers, lacquer is not recommended for this category of patients.
Drug "Lotseril": analogues
Drug on the active substancehas no structural analogues. Drugs similar in their anti-fungal effects are "Anmarin", "Binafin", "Diflucan", "Nizoral", "Fungerbin", "Flucostat". The closest in form and treatment is the medical tool Batrafen. Both varieties “Lotseril” or “Batrafen” are effective for the prevention and treatment of nail mycosis. However, it should be remembered that lacquers will help, if the affected area does not exceed 80 percent of the nail plate.
