Azelaic acid is very popular inpharmaceuticals ingredient that is actively used in the means to combat acne. It is contained in small quantities in the human body, where it is formed in the process of lipid metabolism. For cosmetic and pharmaceutical purposes, it is obtained by biochemical means.
Basic properties
Azelaic acid has several interesting and, of course, useful properties.
First, it has anti-inflammatoryeffect and is able to stop the growth and reproduction of bacteria that play a key role in the development of inflammatory processes in the sebaceous glands. It has a depigmenting, anti-acne effect.
При использовании кремов, содержащих в своем composition of azelaic acid, after a few weeks, the number of bacteria living on the skin is significantly reduced. It is very important that there is no risk of the formation of strains resistant to its effects. Therefore, it does not cause "addiction" at all and is very effective even with prolonged use, even for several months.
Azelaic acid actively inhibitskeratinization of the upper layers of the skin. Due to this quality, it prevents clogging of pores, which means it prevents the appearance of comedones (black dots). In addition, under its influence slows down or completely negated the process of skin pigmentation. It suppresses the production of the natural dark pigment melanin, due to which the effect of light bleaching is obtained.
Azelaic acid is an excellent antioxidant. This property, along with many other effects, makes it an effective cosmetic.
Ointment and cream with azelaic acid, can be used during pregnancy. However, breastfed women should reduce dosage and regular use.
When applied to the skin with azelaic acid, it penetrates the dermis and epidermis, 3.6% of it is absorbed into the bloodstream. It leaves the body almost unchanged, along with the urine.
Remember, if you read that azelaic acid is present in the composition of the product, a cream or lotion will be much more effective than others.
Indications for use
- Youth or common eels.
- Pathological hyperpigmentation. These include pigment spots arising during pregnancy, pigmentation after skin trauma, and other types.
- Seborrheic dermatitis.
- Rosacea.
Side effects
Choosing Pharmaceutical Drugs with Azelaicacid, be sure to pay attention to the percentage of its concentration. This is due to the fact that in high doses it can cause redness and a slight burning of the skin. Therefore, for therapeutic purposes, commonly used means in which its concentration is not more than 20%. In such quantities, it is non-toxic, does not have any side effects, can be used for a long time.
Also worth remembering containing azelaicPharmaceutical ointment acid can not be applied immediately after the procedure of deep peeling. They are not recommended when eating peppered food, alcoholic beverages, with irritated skin or after prolonged exposure to the sun.
Using azelaic acid products,avoid contact with the mucous membranes of the mouth, eyes, nose, ears, etc. In the event of side effects, reduce the dosage or discontinue use for a while.
Industrial use
Also azelaic acid is very wideused in the chemical industry for the production of polyurethanes, rubbers and polyamides. In industrial production, it is added to soap to avoid cracking it.
