/ / Glycosylated hemoglobin and its physiological significance

Glycosylated hemoglobin and its physiological significance

The main criterion for the treatment of diabetesis to achieve a stable physiological concentration of sugar (glucose) in the blood. Blood sugar control can be done at home using portable blood glucose meters, as well as in laboratory conditions. According to the single results of the study of the concentration of glucose in the blood, it is impossible to judge the state of carbohydrate metabolism in the body. Today, a method has been developed for determining the amount of glycated hemoglobin, with the help of which it is possible to assess the state of carbohydrate metabolism. Numerous studies conducted by the DCCT (Diabetes Control Committee and its clinical complications) have found that glucose levels correlate positively with the patient's glycemia. Glycosylated hemoglobin is a qualitative indicator of the effectiveness of therapeutic treatment for diabetes.

Гликозилированный гемоглобин синтезируется в the process of attaching hexose to the nitrogen end sites of the beta chains of hemoglobin globin A1 class (HbA1c). Synthesized HbA1c is deposited in red blood cells (erythrocytes) and stored there for one hundred ten to one hundred thirty days (the lifetime of this cell). Using this indicator, you can determine the level of glycemia in a patient 2–3 months before the start of the study.

Гликозилированный гемоглобин и его концентрация directly proportional to the amount of glucose in the blood. How can I determine its level in the blood? To determine this indicator is best to use special test systems. You can also use other instrumental diagnostic methods: gas-liquid and affinity chromatography, electrophoresis, immunoelectrophoresis, etc. Glycosylated hemoglobin its norm for healthy people is from 4 to 6%. In patients with diabetes mellitus with hyperglycemia, glycated hemoglobin increases two to three times.

Hemoglobin in children has a special meaning.because in a growing body the metabolism is much higher compared to adults. Therefore, parents should know and control the level of hemoglobin in the blood of their baby. It is necessary to prevent iron deficiency anemia. The basis of the development of this disease is the deficiency of the ferum in the body, which is actively involved in the synthesis of hemoglobin. Oxygen starvation adversely affects the development of the nervous, immune and cardiovascular systems. The most susceptible to iron deficiency anemia are children aged 9 months to 5 years.

Today, diabetes control is performed usingAccu-Chek 360 ° forms. Thanks to this form, the attending physician registers the glucose level in the patient’s blood on an empty stomach and after a meal. The most effective way to reduce the concentration of sugar in the blood is the use of long-acting insulin. Using Accu-Chek 360 ° contributes to the proper selection of insulin regimens. Thus, we reduce the level of sugar in the blood to the physiological norm. Many experts argue that using this form of diabetes control can effectively reduce the level of glycated hemoglobin to five to six units in a few months (physiological norm).

Therefore, if you are diagnosed with “sugardiabetes ”, do not despair, give up and dwell on the idea that life is already over. It is necessary to fight for your health. People with diabetes need to constantly monitor the concentration of glucose in the blood. It is much more convenient to carry out these studies at home than to stand in a polyclinic line. Using the modern form of Accu-Chek 360 ° and glucometers, you can easily control your blood sugar level.